Drug profile

The FDA adverse-event record for Dmso

12 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dmso. See the species affected, top reactions, and outcomes below.

12
adverse-event reports
50.0%
death-coded share
Dog
most-reported species
4
INEFFECTIVE, CUSHINGS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
12
Total Reports
6
Deaths Reported
50.0%
Death Rate

Active Ingredients

Dmso

Administration Routes

TopicalIntravenousOralUnknown

Species Affected

Dog 10
Horse 2

Most Affected Breeds

Terrier - Boston 2
Shih Tzu 2
Horse (unknown) 2
Boxer (German Boxer) 2
Bulldog 1
American Pit Bull Terrier 1
Pug 1
Shepherd Dog - German 1

Most Reported Reactions

INEFFECTIVE, CUSHINGS 4
Death by euthanasia 4
Vomiting 4
Diarrhoea 4
Lethargy (see also Central nervous system depression in 'Neurological') 3
Other abnormal test result NOS 3
Malaise 3
Cutaneous calcinosis 2
Lack of efficacy - NOS 2
Weight gain 2
Weight loss 2
Hypothyroidism 2

Outcome Breakdown

Outcome Unknown
6 (50.0%)
Euthanized
3 (25.0%)
Died
3 (25.0%)

Dmso Adverse Event Insights

12 reports name Dmso; 6 recorded a death outcome (50.0% of reported events, not a population-level mortality rate). Active ingredient: Dmso. Administration routes: Topical, Intravenous, Oral, Unknown.

By species: Dog (10 reports), Horse (2 reports). By breed: Terrier - Boston (2), Shih Tzu (2), Horse (unknown) (2).

Leading clinical signs: INEFFECTIVE, CUSHINGS (4), Death by euthanasia (4), Vomiting (4), Diarrhoea (4). Outcome, 12 coded reports: Outcome Unknown leads at 50.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.