Drug profile

The FDA adverse-event record for Diagnostic Reagent(S)

18 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Diagnostic Reagent(S). See the species affected, top reactions, and outcomes below.

18
adverse-event reports
0.0%
death-coded share
Dog
most-reported species
18
INEFFECTIVE, HEARTWORM LARVAE - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
18
Total Reports
0
Deaths Reported
0.0%
Death Rate

Active Ingredients

Diagnostic Reagent(S)

Administration Routes

Unknown

Species Affected

Dog 18

Most Affected Breeds

Shepherd Dog - German 3
Crossbred Canine/dog 3
Poodle - Toy 1
Terrier - Boston 1
Retriever - Golden 1
Terrier (unspecified) 1
Dog (unknown) 1
Pug 1
Spaniel - Springer English 1
Collie - Border 1

Most Reported Reactions

INEFFECTIVE, HEARTWORM LARVAE 18
Lack of efficacy - NOS 7
Drug dose administration interval too long 4

Outcome Breakdown

Ongoing
17 (94.4%)
Outcome Unknown
1 (5.6%)

Diagnostic Reagent(S) Adverse Event Insights

18 reports name Diagnostic Reagent(S); 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). Active ingredient: Diagnostic Reagent(S). Administration route: Unknown.

By species: Dog (18 reports). By breed: Shepherd Dog - German (3), Crossbred Canine/dog (3), Poodle - Toy (1).

Leading clinical signs: INEFFECTIVE, HEARTWORM LARVAE (18), Lack of efficacy - NOS (7), Drug dose administration interval too long (4). Outcome, 18 coded reports: Ongoing leads at 94.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.