Drug profile

The FDA adverse-event record for Dhlpp

47 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dhlpp. See the species affected, top reactions, and outcomes below.

47
adverse-event reports
19.1%
death-coded share
Dog
most-reported species
15
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
47
Total Reports
9
Deaths Reported
19.1%
Death Rate

Active Ingredients

Dhlpp

Administration Routes

SubcutaneousUnknown

Species Affected

Dog 47

Most Affected Breeds

Chihuahua 5
Retriever - Golden 5
Dachshund (unspecified) 3
Shepherd Dog - German 3
Maltese 3
Shih Tzu 3
Terrier - Yorkshire 2
Pug 2
Spitz - German Pomeranian 1
Pit Bull 1

Most Reported Reactions

Vomiting 15
Lethargy (see also Central nervous system depression in Neurological) 9
Anaphylaxis 8
Lethargy (see also Central nervous system depression in 'Neurological') 7
Pale mucous membrane 7
Not eating 7
Death by euthanasia 5
Ataxia 4
Emesis (multiple) 4
Hypercalcaemia 4
Hyperphosphataemia 4
Leucocytosis NOS 4

Outcome Breakdown

Recovered/Normal
24 (51.1%)
Ongoing
13 (27.7%)
Euthanized
5 (10.6%)
Died
4 (8.5%)
Outcome Unknown
1 (2.1%)

Dhlpp Adverse Event Insights

47 reports name Dhlpp; 9 recorded a death outcome (19.1% of reported events, not a population-level mortality rate). Active ingredient: Dhlpp. Administration routes: Subcutaneous, Unknown.

By species: Dog (47 reports). By breed: Chihuahua (5), Retriever - Golden (5), Dachshund (unspecified) (3).

Leading clinical signs: Vomiting (15), Lethargy (see also Central nervous system depression in Neurological) (9), Anaphylaxis (8), Lethargy (see also Central nervous system depression in 'Neurological') (7). Outcome, 47 coded reports: Recovered/Normal leads at 51.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.