Drug profile

The FDA adverse-event record for Deionized Water + Propylene Glycol + Aloe Vera Gel

10 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Deionized Water + Propylene Glycol + Aloe Vera Gel. See the species affected, top reactions, and outcomes below.

10
adverse-event reports
10.0%
death-coded share
Dog
most-reported species
3
Lack of efficacy - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
10
Total Reports
1
Deaths Reported
10.0%
Death Rate

Active Ingredients

Deionized Water + Propylene Glycol + Aloe Vera Gel

Administration Routes

Auricular (Otic)

Species Affected

Dog 9
Cat 1

Most Affected Breeds

Chihuahua 2
Japanese Bobtail 1
Havanese 1
Pinscher - Miniature 1
Spaniel - Boykin 1
Ridgeback - Rhodesian 1
Shepherd (unspecified) 1
Retriever - Labrador 1
Bulldog - American 1

Most Reported Reactions

Lack of efficacy - NOS 3
Anxiety 2
Loss of hearing 2
Nasal discharge 1
Ear discharge 1
Dilated pupils 1
Decreased appetite 1
Scratching 1
Oral cavity disorder NOS 1
Other ear disorder NOS 1
Abnormal radiograph finding 1
Death by euthanasia 1

Outcome Breakdown

Outcome Unknown
4 (40.0%)
Recovered/Normal
4 (40.0%)
Euthanized
1 (10.0%)
Ongoing
1 (10.0%)

Deionized Water + Propylene Glycol + Aloe Vera Gel Adverse Event Insights

10 reports name Deionized Water + Propylene Glycol + Aloe Vera Gel; 1 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). Active ingredient: Deionized Water + Propylene Glycol + Aloe Vera Gel. Administration route: Auricular (Otic).

By species: Dog (9 reports), Cat (1 reports). By breed: Chihuahua (2), Japanese Bobtail (1), Havanese (1).

Leading clinical signs: Lack of efficacy - NOS (3), Anxiety (2), Loss of hearing (2), Nasal discharge (1). Outcome, 10 coded reports: Outcome Unknown leads at 40.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.