Drug profile

The FDA adverse-event record for Dappc Vaccine

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Dappc Vaccine. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
6.7%
death-coded share
Dog
most-reported species
5
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
1
Deaths Reported
6.7%
Death Rate

Active Ingredients

Dappc Vaccine

Administration Routes

UnknownSubcutaneousParenteral

Species Affected

Dog 15

Most Affected Breeds

Retriever - Labrador 3
Hound - Basset 1
Retriever (unspecified) 1
Siberian Husky 1
Boxer (German Boxer) 1
Corso Dog 1
Pit Bull 1
Great Pyrenees 1
Dog (unknown) 1
Crossbred Canine/dog 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 5
Vomiting 5
Ataxia 4
Anorexia 4
Seizure NOS 2
Anaphylaxis 2
Tremor 2
Hyperphosphataemia 2
Hyperglycaemia 2
Lethargy (see also Central nervous system depression in Neurological) 2
Lack of efficacy (bacteria) - Borrelia 2
Weight gain 1

Outcome Breakdown

Outcome Unknown
5 (33.3%)
Ongoing
5 (33.3%)
Recovered/Normal
4 (26.7%)
Died
1 (6.7%)

Dappc Vaccine Adverse Event Insights

15 reports name Dappc Vaccine; 1 recorded a death outcome (6.7% of reported events, not a population-level mortality rate). Active ingredient: Dappc Vaccine. Administration routes: Unknown, Subcutaneous, Parenteral.

By species: Dog (15 reports). By breed: Retriever - Labrador (3), Hound - Basset (1), Retriever (unspecified) (1).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (5), Vomiting (5), Ataxia (4), Anorexia (4). Outcome, 15 coded reports: Outcome Unknown leads at 33.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.