Drug profile

The FDA adverse-event record for Cough Suppressant (Unknown)

34 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Cough Suppressant (Unknown). Species, reactions, and outcomes follow.

#1350 of 2,679
by report volume (all drugs)
34
adverse-event reports
11.8%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Cough Suppressant (Unknown) ranks #1344 of 2679 by total reports (34). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1344
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cough Suppressant (Unknown) has 34 reports now versus 34 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cough Suppressant (Unknown) changes

Signature read: death-coded share at 11.8% is the most distinctive stamp on Cough Suppressant (Unknown)'s FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
34
Total Reports
4
Deaths Reported
11.8%
Death-coded share of reports

Active Ingredients

Cough Suppressant (Unknown)

Administration Routes

OralUnknown

Species Affected

Dog 34

Most Affected Breeds

Crossbred Canine/dog 4
Terrier - Yorkshire 4
Retriever - Labrador 3
Spitz - German Pomeranian 2
Shepherd Dog - Australian 2
Beagle 2
Pug 2
Setter - English 2
Maltese 1
Poodle (unspecified) 1

Most Reported Reactions

Emesis 12
Vomiting 6
Cough 5
Death by euthanasia 3
Lethargy (see also Central nervous system depression in 'Neurological') 3
Panting 2
Shaking 2
Decreased appetite 2
Ataxia 2
Lack of efficacy (endoparasite) - roundworm NOS 2
Blood and lymphatic system disorder NOS 1
Seizure NOS 1

Outcome Breakdown

Recovered/Normal
19 (55.9%)
Outcome Unknown
6 (17.6%)
Ongoing
4 (11.8%)
Euthanized
3 (8.8%)
Recovered with Sequela
1 (2.9%)
Died
1 (2.9%)

Cough Suppressant (Unknown) Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cough Suppressant (Unknown) (#1350 of 2,679 by report volume); death-coded 11.8%. PlainBreed drug row · death-coded share stamp 11.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →