Drug profile

The FDA adverse-event record for Corticosteroid (Unknown)

Name: Corticosteroid (Unknown) - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

27 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Corticosteroid (Unknown). Species, reactions, and outcomes follow.

#1523 of 2,679
by report volume (all drugs): 27
adverse-event reports: 22.2%
death-coded share: Dog
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Corticosteroid (Unknown) ranks #1516 of 2679 by total reports (27). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #1516
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Corticosteroid (Unknown) has 27 reports now versus 27 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Corticosteroid (Unknown) changes

Signature read: Corticosteroid (Unknown)'s 22.2% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

22.2%

Death-coded share of reports

Active Ingredients

Corticosteroid (Unknown)

Administration Routes

UnknownSubcutaneousOralParenteralTopical

Species Affected

Dog 22

Cat 5

Most Affected Breeds

Shih Tzu 5

Domestic Shorthair 4

Retriever - Golden 3

Terrier - Yorkshire 2

Pit Bull 2

Dog (unknown) 1

Crossbred Canine/dog 1

Shepherd Dog - Australian 1

Chihuahua 1

Retriever - Labrador 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 6

Vomiting 5

Lack of efficacy (ectoparasite) - flea 4

Lack of efficacy - NOS 3

Not eating 3

Fever 2

Systemic disorder NOS 2

Death 2

Polyuria 2

NT - Abnormal necropsy finding NOS 2

Death by euthanasia 2

Inappetence 1

Outcome Breakdown

Outcome Unknown

9 (33.3%)

Recovered/Normal

7 (25.9%)

Died

4 (14.8%)

Ongoing

3 (11.1%)

Recovered with Sequela

2 (7.4%)

Euthanized

2 (7.4%)

Corticosteroid (Unknown): high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Corticosteroid (Unknown) (#1523 of 2,679 by report volume); death-coded 22.2%. PlainBreed drug row · death-coded share stamp 22.2% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →