Drug profile

The FDA adverse-event record for Clopidogrel Bisulfate

38 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Clopidogrel Bisulfate. Species, reactions, and outcomes follow.

#1285 of 2,679
by report volume (all drugs)
38
adverse-event reports
42.1%
death-coded share
Dog
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Clopidogrel Bisulfate ranks #1283 of 2679 by total reports (38). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1283
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Clopidogrel Bisulfate has 38 reports now versus 38 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Clopidogrel Bisulfate changes

Signature read: Clopidogrel Bisulfate's 42.1% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
38
Total Reports
16
Deaths Reported
42.1%
Death-coded share of reports

Active Ingredients

Clopidogrel Bisulfate

Administration Routes

OralUnknown

Species Affected

Dog 30
Cat 8

Most Affected Breeds

Domestic Shorthair 6
Poodle (unspecified) 4
Shih Tzu 3
Pug 2
Retriever - Golden 2
Shepherd Dog - Australian 2
Mastiff 1
Beagle 1
Spaniel - Springer (unspecified) 1
Retriever - Labrador 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 17
Immune mediated haemolytic anaemia 17
Anorexia 14
Death by euthanasia 12
Diarrhoea 11
Leucocytosis NOS 11
Pale mucous membrane 10
Anaemia NOS 9
Vomiting 9
Elevated total bilirubin 9
Elevated blood urea nitrogen (BUN) 9
Decreased appetite 6

Outcome Breakdown

Ongoing
15 (39.5%)
Euthanized
10 (26.3%)
Died
6 (15.8%)
Outcome Unknown
5 (13.2%)
Recovered/Normal
2 (5.3%)

Clopidogrel Bisulfate: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Clopidogrel Bisulfate (#1285 of 2,679 by report volume); death-coded 42.1%. PlainBreed drug row · death-coded share stamp 42.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →