Drug profile

The FDA adverse-event record for Ciclosporin

Name: Ciclosporin - FDA Animal Adverse Event Reports
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

10 FDA reports name Ciclosporin, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2554 of 2,679
by report volume (all drugs): 10
adverse-event reports: 0.0%
death-coded share: Unknown
most-reported species

Compiled by PlainBreed

Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Ciclosporin ranks #2536 of 2679 by total reports (10). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1): 97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1): #2536
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Signature read: 10 reports place Ciclosporin in the lower third of FDA AER volume (#2554 of 2,679).

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

Total Reports

Deaths Reported

0.0%

Death-coded share of reports

Active Ingredients

Ciclosporin

Administration Routes

UnknownOral

Species Affected

Unknown 5

Cat 3

Dog 2

Most Affected Breeds

Unknown 5

Persian 1

Crossbred Canine/dog 1

Maine Coon 1

Domestic Shorthair 1

Retriever - Golden 1

Most Reported Reactions

Vomiting 4

Decreased appetite 2

Product defect, product difficult to use/handle (see also 'Drug device difficult to use/handle') 2

UNPALATABLE 2

Cardiac disorder NOS 2

Drooling 1

Pancreatitis NOS 1

Enteritis 1

Urinary tract infection 1

Azotaemia 1

Ureteric disorder 1

Dilated renal pelvis 1

Outcome Breakdown

Ongoing

3 (60.0%)

Recovered/Normal

2 (40.0%)

Ciclosporin: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ciclosporin (#2554 of 2,679 by report volume); death-coded 0.0%. PlainBreed drug row · report volume stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →