Drug profile

The FDA adverse-event record for Chlortetracycline As Calcium Complex (Biomass)

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Chlortetracycline As Calcium Complex (Biomass). See the species affected, top reactions, and outcomes below.

15
adverse-event reports
46.7%
death-coded share
Cattle
most-reported species
5
Lack of efficacy (bacteria) - NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
7
Deaths Reported
46.7%
Death Rate

Active Ingredients

Chlortetracycline As Calcium Complex (Biomass)

Administration Routes

OralUnknown

Species Affected

Cattle 7
Unknown 6
Sheep 1
Horse 1

Most Affected Breeds

Unknown 6
Mixed (Cattle) 3
Cattle (other) 2
Holstein-Friesian also known as Holstein 1
Crossbred Bovine/Cattle 1
Sheep (unknown) 1
Horse (unknown) 1

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 5
Death 4
Color, Abnormal 2
Lack of efficacy (protozoa) - Coccidia 2
Unrelated death 2
Hard, clumping 1
Bloody diarrhoea 1
CULTURE/TITER DATA ABNORMAL 1
Lack of efficacy - NOS 1
NT - Abnormal necropsy finding NOS 1
Pulmonary disorder NOS 1
Abnormal test result 1

Outcome Breakdown

Died
6 (42.9%)
Outcome Unknown
6 (42.9%)
Ongoing
1 (7.1%)
Euthanized
1 (7.1%)

Chlortetracycline As Calcium Complex (Biomass) Adverse Event Insights

15 reports name Chlortetracycline As Calcium Complex (Biomass); 7 recorded a death outcome (46.7% of reported events, not a population-level mortality rate). Active ingredient: Chlortetracycline As Calcium Complex (Biomass). Administration routes: Oral, Unknown.

By species: Cattle (7 reports), Unknown (6 reports), Sheep (1 reports). By breed: Unknown (6), Mixed (Cattle) (3), Cattle (other) (2).

Leading clinical signs: Lack of efficacy (bacteria) - NOS (5), Death (4), Color, Abnormal (2), Lack of efficacy (protozoa) - Coccidia (2). Outcome, 14 coded reports: Died leads at 42.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.