Drug profile

The FDA adverse-event record for Chlortetracycline As Calcium Complex (Biomass)

15 FDA reports name Chlortetracycline As Calcium Complex (Biomass), a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2086 of 2,679
by report volume (all drugs)
15
adverse-event reports
46.7%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Chlortetracycline As Calcium Complex (Biomass) ranks #2072 of 2679 by total reports (15). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#2072
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chlortetracycline As Calcium Complex (Biomass) has 15 reports now versus 15 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chlortetracycline As Calcium Complex (Biomass) changes

Signature read: Chlortetracycline As Calcium Complex (Biomass)'s 46.7% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
7
Deaths Reported
46.7%
Death-coded share of reports

Active Ingredients

Chlortetracycline As Calcium Complex (Biomass)

Administration Routes

OralUnknown

Species Affected

Cattle 7
Unknown 6
Sheep 1
Horse 1

Most Affected Breeds

Unknown 6
Mixed (Cattle) 3
Cattle (other) 2
Holstein-Friesian also known as Holstein 1
Crossbred Bovine/Cattle 1
Sheep (unknown) 1
Horse (unknown) 1

Most Reported Reactions

Lack of efficacy (bacteria) - NOS 5
Death 4
Color, Abnormal 2
Lack of efficacy (protozoa) - Coccidia 2
Unrelated death 2
Hard, clumping 1
Bloody diarrhoea 1
CULTURE/TITER DATA ABNORMAL 1
Lack of efficacy - NOS 1
NT - Abnormal necropsy finding NOS 1
Pulmonary disorder NOS 1
Contamination NOS 1

Outcome Breakdown

Died
6 (42.9%)
Outcome Unknown
6 (42.9%)
Ongoing
1 (7.1%)
Euthanized
1 (7.1%)

Chlortetracycline As Calcium Complex (Biomass): high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chlortetracycline As Calcium Complex (Biomass) (#2086 of 2,679 by report volume); death-coded 46.7%. PlainBreed drug row · death-coded share stamp 46.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →