Drug profile

The FDA adverse-event record for Chlorhexidine Gluconate / Miconazole Nitrate Shampoo

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Chlorhexidine Gluconate / Miconazole Nitrate Shampoo. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
13.3%
death-coded share
Dog
most-reported species
7
Pruritus - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
2
Deaths Reported
13.3%
Death Rate

Active Ingredients

Chlorhexidine Gluconate / Miconazole Nitrate Shampoo

Administration Routes

Topical

Species Affected

Dog 12
Cat 3

Most Affected Breeds

Shih Tzu 2
Terrier - Yorkshire 2
Beagle 1
Abyssinian cat 1
Rottweiler 1
Crossbred Canine/dog 1
Shiba Inu 1
Shepherd Dog - German 1
Retriever - Labrador 1
Domestic Mediumhair 1

Most Reported Reactions

Pruritus 7
Skin lesion NOS 5
Lethargy (see also Central nervous system depression in 'Neurological') 4
Application site alopecia 3
Bacterial skin infection NOS 3
Diarrhoea 2
Digestive tract disorder NOS 2
Vomiting 2
Skin sore 2
Inappetence 2
Swelling NOS 2
Hyperpigmentation 2

Outcome Breakdown

Outcome Unknown
7 (46.7%)
Recovered/Normal
6 (40.0%)
Died
2 (13.3%)

Chlorhexidine Gluconate / Miconazole Nitrate Shampoo Adverse Event Insights

15 reports name Chlorhexidine Gluconate / Miconazole Nitrate Shampoo; 2 recorded a death outcome (13.3% of reported events, not a population-level mortality rate). Active ingredient: Chlorhexidine Gluconate / Miconazole Nitrate Shampoo. Administration route: Topical.

By species: Dog (12 reports), Cat (3 reports). By breed: Shih Tzu (2), Terrier - Yorkshire (2), Beagle (1).

Leading clinical signs: Pruritus (7), Skin lesion NOS (5), Lethargy (see also Central nervous system depression in 'Neurological') (4), Application site alopecia (3). Outcome, 15 coded reports: Outcome Unknown leads at 46.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.