Drug profile

The FDA adverse-event record for Canine Adenovirus Type 2, Strain Manhattan, 12-13-76;Canine Coronavirus, Strain

13 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Canine Adenovirus Type 2, Strain Manhattan, 12-13-76;Canine Coronavirus, Strain. See the species affected, top reactions, and outcomes below.

13
adverse-event reports
23.1%
death-coded share
Dog
most-reported species
5
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
13
Total Reports
3
Deaths Reported
23.1%
Death Rate

Active Ingredients

Canine Adenovirus Type 2, Strain Manhattan, 12-13-76;Canine Coronavirus, Strain

Administration Routes

Subcutaneous

Species Affected

Dog 13

Most Affected Breeds

Retriever - Labrador 3
Chihuahua 2
Shepherd Dog - Belgian Malinois 1
Terrier - Yorkshire 1
Crossbred Canine/dog 1
Dalmatian 1
Siberian Husky 1
Terrier - Jack Russell 1
Spaniel - Springer English 1
Schnauzer - Miniature 1

Most Reported Reactions

Vomiting 5
Lethargy (see also Central nervous system depression in 'Neurological') 2
Weight loss 2
Not eating 2
Eosinopenia 2
Lack of efficacy (virus) - parvovirus (including feline panleukopenia) 2
Death 2
Medication error NOS 2
Decreased appetite 1
Third eyelid extrusion 1
Anal and rectal disorder NOS 1
Anaemia NOS 1

Outcome Breakdown

Ongoing
7 (46.7%)
Recovered/Normal
3 (20.0%)
Outcome Unknown
2 (13.3%)
Died
2 (13.3%)
Euthanized
1 (6.7%)

Canine Adenovirus Type 2, Strain Manhattan, 12-13-76;Canine Coronavirus, Strain Adverse Event Insights

13 reports name Canine Adenovirus Type 2, Strain Manhattan, 12-13-76;Canine Coronavirus, Strain; 3 recorded a death outcome (23.1% of reported events, not a population-level mortality rate). Active ingredient: Canine Adenovirus Type 2, Strain Manhattan, 12-13-76;Canine Coronavirus, Strain. Administration route: Subcutaneous.

By species: Dog (13 reports). By breed: Retriever - Labrador (3), Chihuahua (2), Shepherd Dog - Belgian Malinois (1).

Leading clinical signs: Vomiting (5), Lethargy (see also Central nervous system depression in 'Neurological') (2), Weight loss (2), Not eating (2). Outcome, 15 coded reports: Ongoing leads at 46.7%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.