Drug profile

The FDA adverse-event record for Calcium Gluconate

11 FDA reports name Calcium Gluconate, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#2422 of 2,679
by report volume (all drugs)
11
adverse-event reports
72.7%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Calcium Gluconate ranks #2412 of 2679 by total reports (11). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#2412
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Signature read: Calcium Gluconate's 72.7% death-coded share is among the highest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
8
Deaths Reported
72.7%
Death-coded share of reports

Active Ingredients

Calcium Gluconate

Administration Routes

UnknownIntravenous

Species Affected

Dog 5
Cat 4
Cattle 1
Human 1

Most Affected Breeds

Domestic Longhair 2
Domestic Shorthair 2
Dachshund - Miniature 2
Chihuahua 1
Mixed (Dog) 1
Hound (unspecified) 1
Holstein-Friesian also known as Holstein 1
Unknown 1

Most Reported Reactions

Hyperphosphataemia 6
Death 5
Hyperkalaemia 4
Elevated blood urea nitrogen (BUN) 4
Lethargy (see also Central nervous system depression in Neurological) 4
Dehydration 3
Leucopenia NOS 3
Vomiting 3
Neutropenia 3
Diarrhoea 3
Eosinopenia 3
Hypoproteinaemia 3

Outcome Breakdown

Died
5 (45.5%)
Euthanized
3 (27.3%)
Outcome Unknown
1 (9.1%)
Recovered/Normal
1 (9.1%)
Ongoing
1 (9.1%)

Calcium Gluconate: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Calcium Gluconate (#2422 of 2,679 by report volume); death-coded 72.7%. PlainBreed drug row · death-coded share stamp 72.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →