Drug profile

The FDA adverse-event record for Calcium

42 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Calcium. See the species affected, top reactions, and outcomes below.

42
adverse-event reports
26.2%
death-coded share
Dog
most-reported species
6
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
42
Total Reports
11
Deaths Reported
26.2%
Death Rate

Active Ingredients

Calcium

Administration Routes

OralUnknownIntravenousSubcutaneous

Species Affected

Dog 16
Human 10
Cat 7
Cattle 6
Other 1
Goat 1
Horse 1

Most Affected Breeds

Unknown 11
Domestic Shorthair 5
Holstein-Friesian also known as Holstein 3
Retriever - Labrador 3
Pit Bull 2
Jersey 2
Schnauzer (unspecified) 1
Boxer (German Boxer) 1
Domestic Longhair 1
Terrier - Scottish 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 6
Other abnormal test result NOS 6
Death 6
Vomiting 5
Accidental exposure 5
Dehydration 4
Death by euthanasia 4
Diarrhoea 4
Emesis 3
Anaemia NOS 3
Not eating 3
Icterus 2

Outcome Breakdown

Recovered/Normal
13 (30.2%)
Ongoing
11 (25.6%)
Died
7 (16.3%)
Outcome Unknown
7 (16.3%)
Euthanized
4 (9.3%)
Recovered with Sequela
1 (2.3%)

Calcium Adverse Event Insights

42 reports name Calcium; 11 recorded a death outcome (26.2% of reported events, not a population-level mortality rate). Active ingredient: Calcium. Administration routes: Oral, Unknown, Intravenous, Subcutaneous.

By species: Dog (16 reports), Human (10 reports), Cat (7 reports). By breed: Unknown (11), Domestic Shorthair (5), Holstein-Friesian also known as Holstein (3).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (6), Other abnormal test result NOS (6), Death (6), Vomiting (5). Outcome, 43 coded reports: Recovered/Normal leads at 30.2%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.