Drug profile

The FDA adverse-event record for Bupropion

20 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bupropion. See the species affected, top reactions, and outcomes below.

20
adverse-event reports
5.0%
death-coded share
Human
most-reported species
10
Accidental exposure - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
20
Total Reports
1
Deaths Reported
5.0%
Death Rate

Active Ingredients

Bupropion

Administration Routes

OralUnknown

Species Affected

Human 19
Dog 1

Most Affected Breeds

Unknown 19
Dog (unknown) 1

Most Reported Reactions

Accidental exposure 10
Nervousness 4
Headache 4
Dizziness 3
Feeling anxious 2
Increased heart rate 2
Stomach pain 2
Nausea 2
Diarrhoea 2
Chest discomfort NOS 1
Chest tightness 1
Indigestion 1

Outcome Breakdown

Recovered/Normal
12 (60.0%)
Outcome Unknown
6 (30.0%)
Euthanized
1 (5.0%)
Ongoing
1 (5.0%)

Bupropion Adverse Event Insights

20 reports name Bupropion; 1 recorded a death outcome (5.0% of reported events, not a population-level mortality rate). Active ingredient: Bupropion. Administration routes: Oral, Unknown.

By species: Human (19 reports), Dog (1 reports). By breed: Unknown (19), Dog (unknown) (1).

Leading clinical signs: Accidental exposure (10), Nervousness (4), Headache (4), Dizziness (3). Outcome, 20 coded reports: Recovered/Normal leads at 60.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.