Drug profile

The FDA adverse-event record for Bovine Rhinotracheitis-Virus Diarrhea Vaccine

11 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Rhinotracheitis-Virus Diarrhea Vaccine. See the species affected, top reactions, and outcomes below.

11
adverse-event reports
100.0%
death-coded share
Cattle
most-reported species
11
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
11
Total Reports
11
Deaths Reported
100.0%
Death Rate

Active Ingredients

Bovine Rhinotracheitis-Virus Diarrhea Vaccine

Administration Routes

UnknownParenteral

Species Affected

Cattle 11

Most Affected Breeds

Crossbred Bovine/Cattle 6
Cattle (unknown) 4
Holstein-Friesian also known as Holstein 1

Most Reported Reactions

Death 11
Respiratory tract disorder NOS 6
Behavioural disorder NOS 6
Unclassifiable adverse event 6
Weight gain 4
Digestive tract disorder NOS 4
Acute (interstitial) pneumonia/pleuropneumonia 3
NT - Abnormal necropsy finding NOS 2
Respiratory signs 2
Myocarditis 2
Death by euthanasia 1
Respiratory distress 1

Outcome Breakdown

Died
11 (52.4%)
Outcome Unknown
7 (33.3%)
Ongoing
2 (9.5%)
Euthanized
1 (4.8%)

Bovine Rhinotracheitis-Virus Diarrhea Vaccine Adverse Event Insights

11 reports name Bovine Rhinotracheitis-Virus Diarrhea Vaccine; 11 recorded a death outcome (100.0% of reported events, not a population-level mortality rate). Active ingredient: Bovine Rhinotracheitis-Virus Diarrhea Vaccine. Administration routes: Unknown, Parenteral.

By species: Cattle (11 reports). By breed: Crossbred Bovine/Cattle (6), Cattle (unknown) (4), Holstein-Friesian also known as Holstein (1).

Leading clinical signs: Death (11), Respiratory tract disorder NOS (6), Behavioural disorder NOS (6), Unclassifiable adverse event (6). Outcome, 21 coded reports: Died leads at 52.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.