Drug profile

The FDA adverse-event record for Bovine Respiratory Syncytial Virus, Killed Virus + Bovine Rhinotracheitis Virus, Killed Virus + Bovine Virus Diarrhea Type 1, Killed Virus + Bovine Virus Diarrhea Type 2, Killed Virus + Parainfluenza 3 Virus Vaccine, Killed Virus

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bovine Respiratory Syncytial Virus, Killed Virus + Bovine Rhinotracheitis Virus, Killed Virus + Bovine Virus Diarrhea Type 1, Killed Virus + Bovine Virus Diarrhea Type 2, Killed Virus + Parainfluenza 3 Virus Vaccine, Killed Virus. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
66.7%
death-coded share
Cattle
most-reported species
9
Death - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
10
Deaths Reported
66.7%
Death Rate

Active Ingredients

Bovine Respiratory Syncytial Virus, Killed VirusBovine Rhinotracheitis Virus, Killed VirusBovine Virus Diarrhea Type 1, Killed VirusBovine Virus Diarrhea Type 2, Killed VirusParainfluenza 3 Virus Vaccine, Killed Virus

Administration Routes

SubcutaneousUnknownIntramuscular

Species Affected

Cattle 15

Most Affected Breeds

Cattle (other) 7
Aberdeen Angus 5
Cattle (unknown) 3

Most Reported Reactions

Death 9
Lack of efficacy - NOS 7
Sudden death 1
INEFFECTIVE, WORMS 1
Bronchopneumonia 1
Haemorrhagic diarrhoea 1
Blindness 1
INEFFECTIVE, ANTIBIOTIC 1
Reduced conception rate 1
Stumbling gait 1
Neutrophilia 1
Enteritis 1

Outcome Breakdown

Died
10 (43.5%)
Outcome Unknown
5 (21.7%)
Recovered/Normal
5 (21.7%)
Recovered with Sequela
3 (13.0%)

Bovine Respiratory Syncytial Virus, Killed Virus + Bovine Rhinotracheitis Virus, Killed Virus + Bovine Virus Diarrhea Type 1, Killed Virus + Bovine Virus Diarrhea Type 2, Killed Virus + Parainfluenza 3 Virus Vaccine, Killed Virus Adverse Event Insights

15 reports name Bovine Respiratory Syncytial Virus, Killed Virus + Bovine Rhinotracheitis Virus, Killed Virus + Bovine Virus Diarrhea Type 1, Killed Virus + Bovine Virus Diarrhea Type 2, Killed Virus + Parainfluenza 3 Virus Vaccine, Killed Virus; 10 recorded a death outcome (66.7% of reported events, not a population-level mortality rate). Active ingredients: Bovine Respiratory Syncytial Virus, Killed Virus, Bovine Rhinotracheitis Virus, Killed Virus, Bovine Virus Diarrhea Type 1, Killed Virus, Bovine Virus Diarrhea Type 2, Killed Virus, Parainfluenza 3 Virus Vaccine, Killed Virus. Administration routes: Subcutaneous, Unknown, Intramuscular.

By species: Cattle (15 reports). By breed: Cattle (other) (7), Aberdeen Angus (5), Cattle (unknown) (3).

Leading clinical signs: Death (9), Lack of efficacy - NOS (7), Sudden death (1), INEFFECTIVE, WORMS (1). Outcome, 23 coded reports: Died leads at 43.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.