Drug profile

The FDA adverse-event record for Amoxicillin And Clavulanate Potassium

41 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Amoxicillin And Clavulanate Potassium. See the species affected, top reactions, and outcomes below.

41
adverse-event reports
17.1%
death-coded share
Dog
most-reported species
6
Death by euthanasia - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
41
Total Reports
7
Deaths Reported
17.1%
Death Rate

Active Ingredients

Amoxicillin And Clavulanate Potassium

Administration Routes

OralUnknown

Species Affected

Dog 31
Cat 10

Most Affected Breeds

Domestic Shorthair 5
Retriever - Labrador 4
Chihuahua 3
Dachshund - Miniature 2
Terrier - Boston 2
Maine Coon 2
Terrier - Yorkshire 2
Maltese 2
Siamese 2
Great Pyrenees 2

Most Reported Reactions

Death by euthanasia 6
Vocalisation 5
Vomiting 5
Seizure NOS 5
Ataxia 4
Weight loss 4
Falling 4
Decreased appetite 4
Impaired vision 3
Disorientation 3
Other abnormal test result NOS 3
Hyperglycaemia 3

Outcome Breakdown

Outcome Unknown
18 (43.9%)
Recovered/Normal
10 (24.4%)
Euthanized
6 (14.6%)
Ongoing
5 (12.2%)
Died
1 (2.4%)
Recovered with Sequela
1 (2.4%)

Amoxicillin And Clavulanate Potassium Adverse Event Insights

41 reports name Amoxicillin And Clavulanate Potassium; 7 recorded a death outcome (17.1% of reported events, not a population-level mortality rate). Active ingredient: Amoxicillin And Clavulanate Potassium. Administration routes: Oral, Unknown.

By species: Dog (31 reports), Cat (10 reports). By breed: Domestic Shorthair (5), Retriever - Labrador (4), Chihuahua (3).

Leading clinical signs: Death by euthanasia (6), Vocalisation (5), Vomiting (5), Seizure NOS (5). Outcome, 41 coded reports: Outcome Unknown leads at 43.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.