Reaction profile

The FDA adverse-event record for swollen face (see also skin)

68 FDA adverse-event reports reference swollen face (see also skin) (VeDDRA 1811). See the species, breeds, and drugs most associated with it below.

68
reports citing this reaction
1.5%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
68
Total Reports
1
Deaths
1.5%
Death Rate

Species Most Affected

Dog 59
Cat 5
Human 2
Horse 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 5
Pug 5
Retriever - Labrador 5
Dachshund (unspecified) 4
Shih Tzu 4
Bulldog - English 4
Boxer (German Boxer) 3
Dog (unknown) 3
Terrier - Boston 2
Shepherd Dog - German 2

Associated Drugs

Moxidectin 15
Prednisone 9
Maropitant Citrate 6
Rabies Virus, Kv 6
Bedinvetmab 6
Afoxolaner 6
Diphenhydramine 6
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 5
Milbemycin Oxime + Praziquantel 5
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 5
Dexamethasone 5
Sarolaner 5
Carprofen 5
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 4
Rabies Vaccine 4
Cyclosporine (Ophthalmic) 4
Polysulfated Glycosaminoglycan 4
Anti-Il31 Mab Mcs Lot #1283563 4
Canine Influenza Virus H3N2;Canine Influenza Virus H3N8 3
Fluid Therapy 3

Swollen face (see also Skin) Reaction Insights

68 reports name Swollen face (see also Skin); 1 recorded a death outcome (1.5% of reported events, not a population-level mortality rate). VeDDRA code: 1811.

By species: Dog (59 reports), Cat (5 reports), Human (2 reports). By breed: Domestic Shorthair (5), Pug (5), Retriever - Labrador (5).

Most co-reported drugs: Moxidectin (15 reports), Prednisone (9 reports), Maropitant Citrate (6 reports), Rabies Virus, Kv (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.