Swollen eyelid (see also 'Eyelid disorders' in 'Eye disorders')

Verify with FDA CVM →

VeDDRA Code: 2766

45 adverse event reports referencing this reaction

45
Total Reports
1
Deaths
220.0%
Death Rate

Species Most Affected

Dog 39
Cat 4
Human 1
Cattle 1

Breeds Most Affected

Terrier - Bull - American Pit 6
Retriever - Golden 4
Domestic Shorthair 4
Crossbred Canine/dog 3
Dog (unknown) 3
Pug 2
Terrier - Yorkshire 2
Terrier - Bull 2
Chihuahua 2
Poodle (unspecified) 2

Associated Drugs

Moxidectin 10
Pyrantel Pamoate;Sarolaner 4
Maropitant Citrate 3
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 2
Canine Influenza Virus H3N8;Canine Influenza Virus H3N2 2
Canine Parvovirus Strain Nl-35-D, P.35-D, 8-2-80;Canine Parainfluenza Virus, Str 2
Butorphanol 2
Prednisone 2
Anti-Il31 Mab Mcs Lot #1283563 2
Rabies Virus, 2
Bordetella Bronchiseptica 92B 012992-7 Strain Boehringer Ingelheim 2
Selamectin 2
Afoxolaner 2
Melarsomine Dihydrochloride 2
Nitenpyram 2
Fipronil, S-Methoprene 2
Diphenhydramine 2
Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Modified Live Virus 2
Ketamine Hydrochloride 2
Midazolam 2

Data Summary

Metric Value
Total reports referencing reaction 45
Reports with fatal outcome 1
Case-fatality rate (reported events) 220.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2766.

Swollen eyelid (see also 'Eyelid disorders' in 'Eye disorders') Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 45 adverse event reports that reference Swollen eyelid (see also 'Eyelid disorders' in 'Eye disorders') as a reaction term, including 1 reports with a death outcome — a 220.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2766, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Swollen eyelid (see also 'Eyelid disorders' in 'Eye disorders') appears most frequently in reports for Dog (39 reports), Cat (4 reports), Human (1 reports) — with Dog dominating at 39 entries. Within those species, the breeds most often named alongside this reaction are Terrier - Bull - American Pit (6), Retriever - Golden (4), Domestic Shorthair (4). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Swollen eyelid (see also 'Eyelid disorders' in 'Eye disorders') are Moxidectin (10 reports), Pyrantel Pamoate;Sarolaner (4 reports), Maropitant Citrate (3 reports), Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str (2 reports), with Moxidectin appearing alongside this reaction in 10 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial