Solution/Suspension, crystals

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VeDDRA Code: 93008

676 adverse event reports referencing this reaction

676
Total Reports
3
Deaths
40.0%
Death Rate

Species Most Affected

Unknown 652
Dog 13
Cattle 6
Cat 4
Horse 1

Breeds Most Affected

Unknown 652
Cattle (unknown) 3
Aberdeen Angus 2
Lhasa Apso 2
Crossbred Canine/dog 2
Domestic Shorthair 2
Crossbred Bovine/Cattle 1
Spitz - German Pomeranian 1
Chihuahua 1
Corgi - Welsh Pembroke 1

Associated Drugs

Enrofloxacin 430
Insulin Injectable Vial 44
Furosemide Injection 28
Protamine Zinc Recombinant Human Insulin 25
Ceftiofur Sodium 11
Selamectin 9
Ketamine Hydrochloride 8
Cefovecin 8
Butorphanol Injectable 7
Flunixin Meglumine 6
Doramectin 5
Amitraz 5
Tiletamine Hcl; Zolazapam Hcl 5
Tulathromycin 4
Tilmicosin 4
Dexmedetomidine Hydrochloride 4
Maropitant Citrate 4
Florfenicol Inj Sol 30% W Pg 4
Moxidectin 4
Carprofen 3

Data Summary

Metric Value
Total reports referencing reaction 676
Reports with fatal outcome 3
Case-fatality rate (reported events) 40.0%
Species observed 5
Breeds observed 19
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 93008.

Solution/Suspension, crystals Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 676 adverse event reports that reference Solution/Suspension, crystals as a reaction term, including 3 reports with a death outcome — a 40.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 93008, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Solution/Suspension, crystals appears most frequently in reports for Unknown (652 reports), Dog (13 reports), Cattle (6 reports) — with Unknown dominating at 652 entries. Within those species, the breeds most often named alongside this reaction are Unknown (652), Cattle (unknown) (3), Aberdeen Angus (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Solution/Suspension, crystals are Enrofloxacin (430 reports), Insulin Injectable Vial (44 reports), Furosemide Injection (28 reports), Protamine Zinc Recombinant Human Insulin (25 reports), with Enrofloxacin appearing alongside this reaction in 430 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial