Localised pain NOS (see other SOCs for specific pain)

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VeDDRA Code: 1026

345 adverse event reports referencing this reaction

345
Total Reports
54
Deaths
1570.0%
Death Rate

Species Most Affected

Dog 257
Cat 66
Horse 12
Human 10

Breeds Most Affected

Retriever - Labrador 38
Domestic Shorthair 36
Crossbred Canine/dog 23
Retriever - Golden 15
Shepherd Dog - German 11
Chihuahua 10
Unknown 10
Terrier (unspecified) 10
Terrier - Bull - American Pit 9
Pit Bull 8

Associated Drugs

Bedinvetmab 75
Gabapentin 69
Carprofen 42
Maropitant Citrate 35
Frunevetmab 34
Prednisone 29
Diphenhydramine 21
Oclacitinib Maleate 20
Trilostane 17
Pyrantel Pamoate;Sarolaner 16
Moxidectin 14
Famotidine 14
Buprenorphine 13
Cefovecin 13
Fluralaner 13.64% 12-Week Chew 13
Meloxicam 12
Tigilanol Tiglate 12
Robenacoxib 11
Grapiprant 11
Rabies Virus, Kv 11

Data Summary

Metric Value
Total reports referencing reaction 345
Reports with fatal outcome 54
Case-fatality rate (reported events) 1570.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1026.

Localised pain NOS (see other SOCs for specific pain) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 345 adverse event reports that reference Localised pain NOS (see other SOCs for specific pain) as a reaction term, including 54 reports with a death outcome — a 1570.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1026, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Localised pain NOS (see other SOCs for specific pain) appears most frequently in reports for Dog (257 reports), Cat (66 reports), Horse (12 reports) — with Dog dominating at 257 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (38), Domestic Shorthair (36), Crossbred Canine/dog (23). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Localised pain NOS (see other SOCs for specific pain) are Bedinvetmab (75 reports), Gabapentin (69 reports), Carprofen (42 reports), Maropitant Citrate (35 reports), with Bedinvetmab appearing alongside this reaction in 75 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial