Reaction profile

The FDA adverse-event record for localised pain nos (see other socs for specific pain)

345 FDA adverse-event reports reference localised pain nos (see other socs for specific pain) (VeDDRA 1026). See the species, breeds, and drugs most associated with it below.

345
reports citing this reaction
15.7%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
345
Total Reports
54
Deaths
15.7%
Death Rate

Species Most Affected

Dog 257
Cat 66
Horse 12
Human 10

Breeds Most Affected

Retriever - Labrador 38
Domestic Shorthair 36
Crossbred Canine/dog 23
Retriever - Golden 15
Shepherd Dog - German 11
Chihuahua 10
Unknown 10
Terrier (unspecified) 10
Terrier - Bull - American Pit 9
Pit Bull 8

Associated Drugs

Bedinvetmab 75
Gabapentin 69
Carprofen 42
Maropitant Citrate 35
Frunevetmab 34
Prednisone 29
Diphenhydramine 21
Oclacitinib Maleate 20
Trilostane 17
Pyrantel Pamoate;Sarolaner 16
Moxidectin 14
Famotidine 14
Buprenorphine 13
Cefovecin 13
Fluralaner 13.64% 12-Week Chew 13
Meloxicam 12
Tigilanol Tiglate 12
Robenacoxib 11
Grapiprant 11
Rabies Virus, Kv 11

Localised pain NOS (see other SOCs for specific pain) Reaction Insights

345 reports name Localised pain NOS (see other SOCs for specific pain); 54 recorded a death outcome (15.7% of reported events, not a population-level mortality rate). VeDDRA code: 1026.

By species: Dog (257 reports), Cat (66 reports), Horse (12 reports). By breed: Retriever - Labrador (38), Domestic Shorthair (36), Crossbred Canine/dog (23).

Most co-reported drugs: Bedinvetmab (75 reports), Gabapentin (69 reports), Carprofen (42 reports), Maropitant Citrate (35 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.