Reaction profile
The FDA adverse-event record for lethargy (see also central nervous system depression in neurological)
14,207 FDA adverse-event reports reference lethargy (see also central nervous system depression in neurological) (VeDDRA 1018). See the species, breeds, and drugs most associated with it below.
- 14,207
- reports citing this reaction
- 14.2%
- death-coded share
- Dog
- most-affected species
- Bedinvetmab
- most-associated drug
Species Most Affected
Breeds Most Affected
Associated Drugs
Lethargy (see also Central nervous system depression in Neurological) Reaction Insights
14,207 reports name Lethargy (see also Central nervous system depression in Neurological); 2,016 recorded a death outcome (14.2% of reported events, not a population-level mortality rate). VeDDRA code: 1018.
By species: Dog (10,390 reports), Cat (3,662 reports), Horse (70 reports). By breed: Domestic Shorthair (2,294), Retriever - Labrador (1,061), Crossbred Canine/dog (745).
Most co-reported drugs: Bedinvetmab (1,963 reports), Pyrantel Pamoate;Sarolaner (1,265 reports), Maropitant Citrate (988 reports), Gabapentin (880 reports).
Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.