Reaction profile
The FDA adverse-event record for facial swelling (see also skin)
1,517 FDA adverse-event reports reference facial swelling (see also skin) (VeDDRA 517). See the species, breeds, and drugs most associated with it below.
- 1,517
- reports citing this reaction
- 2.1%
- death-coded share
- Dog
- most-affected species
- Moxidectin
- most-associated drug
Species Most Affected
Breeds Most Affected
Associated Drugs
Facial swelling (see also Skin) Reaction Insights
1,517 reports name Facial swelling (see also Skin); 32 recorded a death outcome (2.1% of reported events, not a population-level mortality rate). VeDDRA code: 517.
By species: Dog (1,415 reports), Cat (88 reports), Human (5 reports). By breed: Retriever - Labrador (144), Terrier - Bull - American Pit (112), Chihuahua (96).
Most co-reported drugs: Moxidectin (677 reports), Rabies Virus, Kv (196 reports), Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str (131 reports), Maropitant Citrate (129 reports).
Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.