Circling - behavioural disorder (see also Neurological disorders)

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VeDDRA Code: 2611

147 adverse event reports referencing this reaction

147
Total Reports
25
Deaths
1700.0%
Death Rate

Species Most Affected

Dog 107
Cat 37
Cattle 2
Horse 1

Breeds Most Affected

Domestic Shorthair 19
Crossbred Canine/dog 12
Chihuahua 9
Shepherd Dog - German 7
Cat (unknown) 6
Retriever - Labrador 6
Shih Tzu 6
Terrier - Yorkshire 5
Retriever - Golden 4
Dog (unknown) 4

Associated Drugs

Bedinvetmab 37
Buprenorphine 27
Gabapentin 15
Lotilaner 10
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 9
Maropitant Citrate 9
Robenacoxib 9
Fluralaner 13.64% 12-Week Chew 8
Carprofen 7
Pyrantel Pamoate;Sarolaner 6
Dexmedetomidine 6
Anti-Il31 Mab Mcs Lot #1283563 5
Ketamine 5
Prednisone 5
Polysulfated Glycosaminoglycan 4
Frunevetmab 4
Milbemycin Oxime + Praziquantel 4
Alfaxalone 4
Mirtazapine 4
Antibiotic (Unknown) 3

Data Summary

Metric Value
Total reports referencing reaction 147
Reports with fatal outcome 25
Case-fatality rate (reported events) 1700.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2611.

Circling - behavioural disorder (see also Neurological disorders) Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 147 adverse event reports that reference Circling - behavioural disorder (see also Neurological disorders) as a reaction term, including 25 reports with a death outcome — a 1700.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2611, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Circling - behavioural disorder (see also Neurological disorders) appears most frequently in reports for Dog (107 reports), Cat (37 reports), Cattle (2 reports) — with Dog dominating at 107 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (19), Crossbred Canine/dog (12), Chihuahua (9). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Circling - behavioural disorder (see also Neurological disorders) are Bedinvetmab (37 reports), Buprenorphine (27 reports), Gabapentin (15 reports), Lotilaner (10 reports), with Bedinvetmab appearing alongside this reaction in 37 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial