Drug profile

The FDA adverse-event record for Zinc

14 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Zinc. See the species affected, top reactions, and outcomes below.

14
adverse-event reports
28.6%
death-coded share
Dog
most-reported species
3
Elevated serum alkaline phosphatase (ALP) - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
14
Total Reports
4
Deaths Reported
28.6%
Death Rate

Active Ingredients

Zinc

Administration Routes

UnknownOralOther

Species Affected

Dog 11
Human 1
Cat 1
Cattle 1

Most Affected Breeds

Crossbred Canine/dog 2
Siberian Husky 2
Hound (unspecified) 2
Terrier - Bull - Staffordshire 1
Unknown 1
Catahoula Leopard Dog 1
Domestic Longhair 1
Holstein-Friesian also known as Holstein 1
Terrier - West Highland White 1
Deutsche Dogge, Great Dane 1

Most Reported Reactions

Elevated serum alkaline phosphatase (ALP) 3
Death by euthanasia 3
Vomiting 2
Anorexia 2
Lameness 2
Loose stool 2
Weight loss 2
Diarrhoea 2
Soft stool 2
Elevated liver enzymes 1
Elevated alanine aminotransferase (ALT) 1
Burning sensation of the throat 1

Outcome Breakdown

Ongoing
5 (33.3%)
Recovered/Normal
4 (26.7%)
Euthanized
3 (20.0%)
Outcome Unknown
2 (13.3%)
Died
1 (6.7%)

Zinc Adverse Event Insights

14 reports name Zinc; 4 recorded a death outcome (28.6% of reported events, not a population-level mortality rate). Active ingredient: Zinc. Administration routes: Unknown, Oral, Other.

By species: Dog (11 reports), Human (1 reports), Cat (1 reports). By breed: Crossbred Canine/dog (2), Siberian Husky (2), Hound (unspecified) (2).

Leading clinical signs: Elevated serum alkaline phosphatase (ALP) (3), Death by euthanasia (3), Vomiting (2), Anorexia (2). Outcome, 15 coded reports: Ongoing leads at 33.3%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.