Drug profile

The FDA adverse-event record for Unspecified Fluids

299 FDA reports name Unspecified Fluids, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#422 of 2,679
by report volume (all drugs)
299
adverse-event reports
32.1%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Unspecified Fluids ranks #422 of 2679 by total reports (299) and #115 of 1130 by death-coded share (32.1%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#422
This drug, reports of 2679
#115
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Unspecified Fluids has 299 reports now versus 298 in that prior snapshot: 1 more (0.3%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Unspecified Fluids changes

Signature read: death-coded report count at 96 is the most distinctive stamp on Unspecified Fluids's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
299
Total Reports
96
Deaths Reported
32.1%
Death-coded share of reports

Active Ingredients

Unspecified Fluids

Administration Routes

SubcutaneousIntravenousUnknownOralParenteral

Species Affected

Dog 191
Cat 106
Alpaca 1
Other 1

Most Affected Breeds

Domestic Shorthair 69
Retriever - Labrador 35
Chihuahua 12
Shih Tzu 9
Domestic Longhair 8
Retriever - Golden 7
Crossbred Canine/dog 6
Terrier - Yorkshire 6
Cat (unknown) 6
Dachshund (unspecified) 6

Most Reported Reactions

Vomiting 74
Lethargy (see also Central nervous system depression in Neurological) 74
Diarrhoea 61
Not eating 50
Death 49
Death by euthanasia 46
Anorexia 42
Elevated blood urea nitrogen (BUN) 35
Dehydration 34
Weight loss 34
Lethargy (see also Central nervous system depression in 'Neurological') 33
Elevated alanine aminotransferase (ALT) 32

Outcome Breakdown

Ongoing
89 (29.8%)
Outcome Unknown
59 (19.7%)
Recovered/Normal
54 (18.1%)
Died
50 (16.7%)
Euthanized
46 (15.4%)
Recovered with Sequela
1 (0.3%)

Unspecified Fluids: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Unspecified Fluids, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (299 here).

Similar death-coded share

Nearest other drugs by death-coded share (32.1% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Unspecified Fluids (#422 of 2,679 by report volume); death-coded 32.1%. PlainBreed drug row · death-coded report count stamp 96 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →