Drug profile

The FDA adverse-event record for Unspecified Fluids

273 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Unspecified Fluids. See the species affected, top reactions, and outcomes below.

273
adverse-event reports
34.4%
death-coded share
Dog
most-reported species
70
Lethargy (see also Central nervous system depression in Neurological) - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
273
Total Reports
94
Deaths Reported
34.4%
Death Rate

Active Ingredients

Unspecified Fluids

Administration Routes

SubcutaneousIntravenousUnknownOralParenteral

Species Affected

Dog 180
Cat 91
Alpaca 1
Other 1

Most Affected Breeds

Domestic Shorthair 56
Retriever - Labrador 34
Chihuahua 12
Shih Tzu 8
Domestic Longhair 7
Terrier - Yorkshire 6
Cat (unknown) 6
Dachshund (unspecified) 6
Spitz - German Pomeranian 6
Retriever - Golden 6

Most Reported Reactions

Lethargy (see also Central nervous system depression in Neurological) 70
Vomiting 68
Death 47
Not eating 47
Death by euthanasia 46
Diarrhoea 45
Anorexia 40
Dehydration 34
Lethargy (see also Central nervous system depression in 'Neurological') 33
Weight loss 33
Decreased appetite 32
Elevated alanine aminotransferase (ALT) 31

Outcome Breakdown

Ongoing
74 (27.1%)
Outcome Unknown
53 (19.4%)
Recovered/Normal
51 (18.7%)
Died
48 (17.6%)
Euthanized
46 (16.8%)
Recovered with Sequela
1 (0.4%)

Unspecified Fluids Adverse Event Insights

273 reports name Unspecified Fluids; 94 recorded a death outcome (34.4% of reported events, not a population-level mortality rate). Active ingredient: Unspecified Fluids. Administration routes: Subcutaneous, Intravenous, Unknown, Oral.

By species: Dog (180 reports), Cat (91 reports), Alpaca (1 reports). By breed: Domestic Shorthair (56), Retriever - Labrador (34), Chihuahua (12).

Leading clinical signs: Lethargy (see also Central nervous system depression in Neurological) (70), Vomiting (68), Death (47), Not eating (47). Outcome, 273 coded reports: Ongoing leads at 27.1%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.