Drug profile

The FDA adverse-event record for Prednisolone Trimeprazine Tartrate

481 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Prednisolone Trimeprazine Tartrate. See the species affected, top reactions, and outcomes below.

481
adverse-event reports
3.1%
death-coded share
Dog
most-reported species
199
Emesis - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
481
Total Reports
15
Deaths Reported
3.1%
Death Rate

Active Ingredients

Prednisolone Trimeprazine Tartrate

Administration Routes

OralUnknown

Species Affected

Dog 477
Cat 2
Unknown 2

Most Affected Breeds

Retriever - Labrador 40
Shih Tzu 37
Terrier - Yorkshire 35
Chihuahua 34
Retriever - Golden 22
Terrier (unspecified) 19
Pit Bull 15
Terrier - Jack Russell 14
Crossbred Canine/dog 14
Bichon Frise 12

Most Reported Reactions

Emesis 199
Vomiting 61
Lethargy (see also Central nervous system depression in 'Neurological') 57
Lack of efficacy - NOS 49
Lack of efficacy (ectoparasite) - flea 31
Diarrhoea 25
Seizure NOS 19
Other abnormal test result NOS 18
INEFFECTIVE, HEARTWORM LARVAE 15
Anorexia 14
Ataxia 14
Itching 13

Outcome Breakdown

Recovered/Normal
296 (61.8%)
Outcome Unknown
106 (22.1%)
Recovered with Sequela
39 (8.1%)
Ongoing
23 (4.8%)
Euthanized
8 (1.7%)
Died
7 (1.5%)

Prednisolone Trimeprazine Tartrate Adverse Event Insights

481 reports name Prednisolone Trimeprazine Tartrate; 15 recorded a death outcome (3.1% of reported events, not a population-level mortality rate). Active ingredient: Prednisolone Trimeprazine Tartrate. Administration routes: Oral, Unknown.

By species: Dog (477 reports), Cat (2 reports), Unknown (2 reports). By breed: Retriever - Labrador (40), Shih Tzu (37), Terrier - Yorkshire (35).

Leading clinical signs: Emesis (199), Vomiting (61), Lethargy (see also Central nervous system depression in 'Neurological') (57), Lack of efficacy - NOS (49). Outcome, 479 coded reports: Recovered/Normal leads at 61.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.