Drug profile

The FDA adverse-event record for Pradofloxacin

592 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Pradofloxacin. See the species affected, top reactions, and outcomes below.

592
adverse-event reports
13.3%
death-coded share
Cat
most-reported species
67
Behavioural disorder NOS - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
592
Total Reports
79
Deaths Reported
13.3%
Death Rate

Active Ingredients

Pradofloxacin

Administration Routes

OralUnknownParenteralTopicalOtherSubcutaneous

Species Affected

Cat 483
Unknown 91
Dog 12
Human 3
Cattle 2
Fallow 1

Most Affected Breeds

Domestic Shorthair 258
Unknown 95
Cat (unknown) 65
Domestic Longhair 46
Domestic Mediumhair 38
Siamese 16
Maine Coon 13
Persian 10
Cat (other) 7
Oriental 4

Most Reported Reactions

Behavioural disorder NOS 67
Vomiting 58
Hypersalivation 49
Lethargy (see also Central nervous system depression in 'Neurological') 48
Anorexia 47
Diarrhoea 46
Death by euthanasia 41
Death 38
Uncoded sign 35
Weight loss 34
Other abnormal test result NOS 33
Blindness 31

Outcome Breakdown

Outcome Unknown
208 (41.4%)
Recovered/Normal
157 (31.2%)
Ongoing
55 (10.9%)
Died
40 (8.0%)
Euthanized
40 (8.0%)
Recovered with Sequela
3 (0.6%)

Pradofloxacin Adverse Event Insights

592 reports name Pradofloxacin; 79 recorded a death outcome (13.3% of reported events, not a population-level mortality rate). Active ingredient: Pradofloxacin. Administration routes: Oral, Unknown, Parenteral, Topical.

By species: Cat (483 reports), Unknown (91 reports), Dog (12 reports). By breed: Domestic Shorthair (258), Unknown (95), Cat (unknown) (65).

Leading clinical signs: Behavioural disorder NOS (67), Vomiting (58), Hypersalivation (49), Lethargy (see also Central nervous system depression in 'Neurological') (48). Outcome, 503 coded reports: Outcome Unknown leads at 41.4%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.