Phenylpropanolamine
803 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
803
Total Reports
120
Deaths Reported
1490.0%
Death Rate
Active Ingredients
Phenylpropanolamine
Administration Routes
OralUnknownTopicalParenteral
Species Affected
Dog 793
Human 6
Unknown 4
Most Affected Breeds
Retriever - Labrador 115
Crossbred Canine/dog 99
Shepherd Dog - German 45
Boxer (German Boxer) 33
Terrier - Yorkshire 21
Doberman Pinscher 21
Dog (unknown) 17
Terrier - Bull - American Pit 17
Mixed (Dog) 16
Collie - Border 15
Most Reported Reactions
Vomiting 153
Lethargy (see also Central nervous system depression in 'Neurological') 130
Accidental exposure 90
Death by euthanasia 82
Diarrhoea 79
Anorexia 73
Emesis 69
Agitation 65
Elevated alanine aminotransferase (ALT) 55
Panting 48
Ataxia 45
Urinary incontinence 43
Outcome Breakdown
Recovered/Normal
281 (36.0%)
Ongoing
216 (27.7%)
Outcome Unknown
158 (20.2%)
Euthanized
76 (9.7%)
Died
45 (5.8%)
Recovered with Sequela
5 (0.6%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.