Drug profile

The FDA adverse-event record for Monensin Sodium

2,561 FDA reports name Monensin Sodium, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#87 of 2,679
by report volume (all drugs)
2,561
adverse-event reports
51.8%
death-coded share
Cattle
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Monensin Sodium ranks #87 of 2679 by total reports (2,561) and #56 of 1130 by death-coded share (51.8%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#87
This drug, reports of 2679
#56
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Monensin Sodium has 2,561 reports now versus 2,537 in that prior snapshot: 24 more (0.9%).

Report change
+24
Death-coded reports
+6
Death-coded share
−0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Monensin Sodium changes

Signature read: death-coded report count at 1,326 is the most distinctive stamp on Monensin Sodium's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
2,561
Total Reports
1,326
Deaths Reported
51.8%
Death-coded share of reports

Active Ingredients

Monensin Sodium

Administration Routes

OralUnknownRespiratory (Inhalation)OtherIntraocularOphthalmic

Species Affected

Cattle 1,922
Turkey 194
Horse 114
Chicken 94
Unknown 75
Goat 42
Sheep 33
Pig 30
Human 16
Dog 15

Most Affected Breeds

Holstein-Friesian also known as Holstein 862
Cattle (unknown) 493
Turkey (unknown) 171
Crossbred Bovine/Cattle 134
Mixed (Cattle) 110
Aberdeen Angus 105
Unknown 103
Cattle (other) 93
Jersey 90
Horse (unknown) 77

Most Reported Reactions

Death 1,170
Diarrhoea 248
Milk production decrease 207
Decreased appetite 202
Lack of efficacy (protozoa) - Coccidia 197
Not eating 184
Lack of efficacy - NOS 175
NT - Abnormal necropsy finding NOS 155
Anorexia 149
Recumbency 133
Loose stool 126
Alteration of milk quality 125

Outcome Breakdown

Died
1,294 (40.0%)
Outcome Unknown
1,109 (34.3%)
Recovered/Normal
429 (13.3%)
Ongoing
228 (7.0%)
Recovered with Sequela
90 (2.8%)
Euthanized
87 (2.7%)

Monensin Sodium: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Monensin Sodium, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar death-coded share

Nearest other drugs by death-coded share (51.8% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Monensin Sodium (#87 of 2,679 by report volume); death-coded 51.8%. PlainBreed drug row · death-coded report count stamp 1,326 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →