Drug profile

The FDA adverse-event record for Maropitant Citrate

14,009 FDA reports name Maropitant Citrate, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#19 of 2,679
by report volume (all drugs)
14,009
adverse-event reports
21.4%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Maropitant Citrate ranks #19 of 2679 by total reports (14,009) and #216 of 1130 by death-coded share (21.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#19
This drug, reports of 2679
#216
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Maropitant Citrate has 14,009 reports now versus 13,597 in that prior snapshot: 412 more (3.0%).

Report change
+412
Death-coded reports
+73
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Maropitant Citrate changes

Signature read: death-coded report count at 3,004 is the most distinctive stamp on Maropitant Citrate's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
14,009
Total Reports
3,004
Deaths Reported
21.4%
Death-coded share of reports

Active Ingredients

Maropitant Citrate

Administration Routes

SubcutaneousUnknownOralIntravenousParenteralOtherIntramuscularOphthalmicNasalTopical

Species Affected

Dog 9,752
Cat 3,362
Unknown 712
Human 170
Other 4
Rabbit 4
Monkey 2
Horse 1
Wolf 1
Pig 1

Most Affected Breeds

Domestic Shorthair 2,001
Retriever - Labrador 1,144
Unknown 909
Chihuahua 494
Retriever - Golden 434
Terrier - Yorkshire 428
Dog (unknown) 371
Crossbred Canine/dog 352
Shih Tzu 350
Terrier - Bull - American Pit 320

Most Reported Reactions

Vomiting 3,962
Lethargy (see also Central nervous system depression in 'Neurological') 2,283
Anorexia 1,918
Diarrhoea 1,881
Death by euthanasia 1,564
Lack of efficacy - NOS 1,507
Not eating 1,439
Death 1,339
Lethargy (see also Central nervous system depression in Neurological) 1,269
Elevated alanine aminotransferase (ALT) 1,209
Other abnormal test result NOS 1,186
Weight loss 995

Outcome Breakdown

Ongoing
5,595 (42.0%)
Recovered/Normal
2,658 (19.9%)
Outcome Unknown
2,042 (15.3%)
Euthanized
1,569 (11.8%)
Died
1,444 (10.8%)
Recovered with Sequela
26 (0.2%)

Maropitant Citrate: high death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Maropitant Citrate, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

Similar report volume

Nearest other drugs by FDA report count (14,009 here).

Similar death-coded share

Nearest other drugs by death-coded share (21.4% here), distinct from the volume row.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Maropitant Citrate (#19 of 2,679 by report volume); death-coded 21.4%. PlainBreed drug row · death-coded report count stamp 3,004 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →