Drug profile

The FDA adverse-event record for Maropitant Citrate

13,003 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Maropitant Citrate. See the species affected, top reactions, and outcomes below.

13,003
adverse-event reports
21.6%
death-coded share
Dog
most-reported species
3,768
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
13,003
Total Reports
2,813
Deaths Reported
21.6%
Death Rate

Active Ingredients

Maropitant Citrate

Administration Routes

SubcutaneousUnknownOralIntravenousParenteralOtherIntramuscularOphthalmicNasalTopical

Species Affected

Dog 9,157
Cat 3,003
Unknown 671
Human 159
Other 4
Rabbit 4
Monkey 2
Horse 1
Wolf 1
Pig 1

Most Affected Breeds

Domestic Shorthair 1,788
Retriever - Labrador 1,093
Unknown 850
Chihuahua 461
Terrier - Yorkshire 404
Retriever - Golden 404
Dog (unknown) 361
Shih Tzu 330
Crossbred Canine/dog 311
Terrier - Bull - American Pit 300

Most Reported Reactions

Vomiting 3,768
Lethargy (see also Central nervous system depression in 'Neurological') 2,284
Anorexia 1,834
Diarrhoea 1,725
Death by euthanasia 1,466
Lack of efficacy - NOS 1,353
Not eating 1,246
Death 1,243
Other abnormal test result NOS 1,110
Elevated alanine aminotransferase (ALT) 1,102
Lethargy (see also Central nervous system depression in Neurological) 988
Weight loss 919

Outcome Breakdown

Ongoing
5,174 (41.9%)
Recovered/Normal
2,473 (20.0%)
Outcome Unknown
1,872 (15.1%)
Euthanized
1,471 (11.9%)
Died
1,348 (10.9%)
Recovered with Sequela
25 (0.2%)

Maropitant Citrate Adverse Event Insights

13,003 reports name Maropitant Citrate; 2,813 recorded a death outcome (21.6% of reported events, not a population-level mortality rate). Active ingredient: Maropitant Citrate. Administration routes: Subcutaneous, Unknown, Oral, Intravenous.

By species: Dog (9,157 reports), Cat (3,003 reports), Unknown (671 reports). By breed: Domestic Shorthair (1,788), Retriever - Labrador (1,093), Unknown (850).

Leading clinical signs: Vomiting (3,768), Lethargy (see also Central nervous system depression in 'Neurological') (2,284), Anorexia (1,834), Diarrhoea (1,725). Outcome, 12,363 coded reports: Ongoing leads at 41.9%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.