Drug profile

The FDA adverse-event record for Maropitant

1,899 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Maropitant. See the species affected, top reactions, and outcomes below.

1,899
adverse-event reports
21.4%
death-coded share
Dog
most-reported species
278
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
1,899
Total Reports
407
Deaths Reported
21.4%
Death Rate

Active Ingredients

Maropitant

Administration Routes

SubcutaneousOralUnknownIntravenousParenteralIntramuscularOphthalmicTopicalOtherRespiratory (Inhalation)

Species Affected

Dog 1,417
Cat 381
Unknown 77
Human 19
Other 3
Rabbit 2

Most Affected Breeds

Crossbred Canine/dog 170
Retriever - Labrador 156
Domestic Shorthair 145
Domestic (unspecified) 127
Unknown 110
Dog (unknown) 82
Retriever - Golden 59
Terrier - Yorkshire 46
Chihuahua 43
Shepherd Dog - German 43

Most Reported Reactions

Vomiting 278
Anorexia 225
Death by euthanasia 218
Death 182
Diarrhoea 181
INEFFECTIVE, ANTIEMETIC 159
Elevated alanine aminotransferase (ALT) 146
Depression 137
Weight loss 120
Lethargy (see also Central nervous system depression in 'Neurological') 120
Abnormal radiograph finding 118
Hypersalivation 116

Outcome Breakdown

Recovered/Normal
290 (26.5%)
Died
274 (25.0%)
Outcome Unknown
213 (19.5%)
Ongoing
175 (16.0%)
Euthanized
134 (12.2%)
Recovered with Sequela
9 (0.8%)

Maropitant Adverse Event Insights

1,899 reports name Maropitant; 407 recorded a death outcome (21.4% of reported events, not a population-level mortality rate). Active ingredient: Maropitant. Administration routes: Subcutaneous, Oral, Unknown, Intravenous.

By species: Dog (1,417 reports), Cat (381 reports), Unknown (77 reports). By breed: Crossbred Canine/dog (170), Retriever - Labrador (156), Domestic Shorthair (145).

Leading clinical signs: Vomiting (278), Anorexia (225), Death by euthanasia (218), Death (182). Outcome, 1,095 coded reports: Recovered/Normal leads at 26.5%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.