Drug profile

The FDA adverse-event record for Lime Sulfur

15 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Lime Sulfur. See the species affected, top reactions, and outcomes below.

15
adverse-event reports
13.3%
death-coded share
Dog
most-reported species
6
Lethargy (see also Central nervous system depression in 'Neurological') - top reaction
Verify with FDA CVM →
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
15
Total Reports
2
Deaths Reported
13.3%
Death Rate

Active Ingredients

Lime Sulfur

Administration Routes

TopicalUnknown

Species Affected

Dog 8
Cat 7

Most Affected Breeds

Domestic Shorthair 5
Deutsche Dogge, Great Dane 1
Cat (other) 1
Spaniel - Boykin 1
Terrier - Bull - American Pit 1
Chihuahua 1
Bulldog 1
Domestic Longhair 1
Shih Tzu 1
Pug 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 6
Lack of efficacy - NOS 3
Emesis 2
Application site pruritus 2
Not eating 2
Death by euthanasia 2
Seizure NOS 2
Diarrhoea 1
Vomiting 1
Uveitis 1
Conjunctivitis 1
Lack of efficacy (ectoparasite) - mite NOS 1

Outcome Breakdown

Ongoing
9 (60.0%)
Recovered/Normal
2 (13.3%)
Outcome Unknown
2 (13.3%)
Euthanized
2 (13.3%)

Lime Sulfur Adverse Event Insights

15 reports name Lime Sulfur; 2 recorded a death outcome (13.3% of reported events, not a population-level mortality rate). Active ingredient: Lime Sulfur. Administration routes: Topical, Unknown.

By species: Dog (8 reports), Cat (7 reports). By breed: Domestic Shorthair (5), Deutsche Dogge, Great Dane (1), Cat (other) (1).

Leading clinical signs: Lethargy (see also Central nervous system depression in 'Neurological') (6), Lack of efficacy - NOS (3), Emesis (2), Application site pruritus (2). Outcome, 15 coded reports: Ongoing leads at 60.0%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.