L-Asparaginase

16 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
16
Total Reports
8
Deaths Reported
5000.0%
Death Rate

Active Ingredients

L-Asparaginase

Administration Routes

UnknownIntravenousSubcutaneousParenteral

Species Affected

Dog 15
Cat 1

Most Affected Breeds

Dog (unknown) 2
Spaniel (unspecified) 2
Retriever - Labrador 2
Boxer (German Boxer) 1
Crossbred Canine/dog 1
Terrier - Jack Russell 1
Chinese Crested Dog (unspecified) 1
Retriever - Golden 1
Pit Bull 1
Plott 1

Most Reported Reactions

Death by euthanasia 7
Diarrhoea 7
Anorexia 5
Lack of efficacy - NOS 5
Vomiting 4
Weight loss 4
Lethargy (see also Central nervous system depression in Neurological) 4
Acute renal failure 2
Emesis (multiple) 2
Enlarged lymph nodes (generalised) 2
Thrombocytopenia 2
Elevated creatinine 2

Outcome Breakdown

Euthanized
7 (43.8%)
Ongoing
5 (31.3%)
Outcome Unknown
2 (12.5%)
Recovered/Normal
1 (6.3%)
Died
1 (6.3%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.