Ivermectin, Pyrantel Pamoate, Praziquantel
854 adverse event reports submitted to the FDA
Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
854
Total Reports
27
Deaths Reported
320.0%
Death Rate
Active Ingredients
Ivermectin, Pyrantel Pamoate, Praziquantel
Administration Routes
OralUnknownIntrauterineTopical
Species Affected
Dog 807
Unknown 40
Human 5
Cat 1
Rabbit 1
Most Affected Breeds
Crossbred Canine/dog 103
Retriever - Labrador 91
Dog (unknown) 68
Unknown 45
Shepherd Dog - German 40
Terrier - Yorkshire 33
Retriever - Golden 32
Chihuahua 30
Shih Tzu 29
Poodle (unspecified) 23
Most Reported Reactions
Vomiting 255
INEFFECTIVE, HEARTWORM LARVAE 203
INEFFECTIVE, ASCARIDS NOS 84
Lack of efficacy (endoparasite) - hookworm 84
Depression 81
Diarrhoea 62
Lack of efficacy (endoparasite) - tapeworm 53
Underfilling, Package 32
Anorexia 30
Accidental exposure 29
Convulsion 20
Lack of efficacy (endoparasite) - heartworm 18
Outcome Breakdown
Outcome Unknown
32 (47.8%)
Died
27 (40.3%)
Recovered/Normal
5 (7.5%)
Ongoing
3 (4.5%)
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.