Ivermectin & Pyrantel

575 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

575

Total Reports

Deaths Reported

280.0%

Death Rate

Active Ingredients

Ivermectin & Pyrantel

Administration Routes

OralUnknownOphthalmic

Species Affected

Dog 574

Cat 1

Most Affected Breeds

Retriever - Labrador 88

Shepherd Dog - German 35

Chihuahua 29

Retriever - Golden 26

Crossbred Canine/dog 18

Terrier - Bull - American Pit 17

Beagle 15

Dog (unknown) 15

Terrier (unspecified) 14

Dachshund (unspecified) 13

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 209

Vomiting 74

Seizure NOS 53

Lethargy (see also Central nervous system depression in 'Neurological') 45

Lack of efficacy - NOS 38

Diarrhoea 28

INEFFECTIVE, HEARTWORM LARVAE 27

Ataxia 24

INEFFECTIVE, HEARTWORM ADULTS 24

Anorexia 22

Elevated alanine aminotransferase (ALT) 19

Tremor 18

Outcome Breakdown

Ongoing

402 (69.8%)

Outcome Unknown

87 (15.1%)

Recovered/Normal

71 (12.3%)

Euthanized

9 (1.6%)

Died

7 (1.2%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.