Ivermectin, Pyrantel

12,042 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

12,042

Total Reports

134

Deaths Reported

110.0%

Death Rate

Active Ingredients

Ivermectin, Pyrantel

Administration Routes

OralUnknownSubcutaneousTopicalIntramuscularRectal

Species Affected

Dog 11,008

Unknown 1,006

Cat 14

Human 12

Other 1

Ferret 1

Most Affected Breeds

Crossbred Canine/dog 2,930

Retriever - Labrador 1,766

Unknown 1,020

Shepherd Dog - German 515

Retriever - Golden 445

Dog (unknown) 409

Boxer (German Boxer) 274

Beagle 245

Dachshund (unspecified) 211

Chihuahua 189

Most Reported Reactions

INEFFECTIVE, HEARTWORM LARVAE 5,224

Lack of efficacy (endoparasite) - hookworm 2,185

INEFFECTIVE, ASCARIDS NOS 1,460

Vomiting 1,164

Diarrhoea 544

Tablets, Abnormal 511

Depression 482

Containers, Damaged 276

Anorexia 272

Convulsion 176

Underfilling, Package 173

Accidental exposure 143

Outcome Breakdown

Outcome Unknown

261 (44.8%)

Died

132 (22.7%)

Recovered/Normal

113 (19.4%)

Ongoing

62 (10.7%)

Recovered with Sequela

12 (2.1%)

Euthanized

2 (0.3%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.