Ivermectin

11,677 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

11,677

Total Reports

626

Deaths Reported

540.0%

Death Rate

Active Ingredients

Ivermectin

Administration Routes

OralUnknownTopicalSubcutaneousOtherAuricular (Otic)ParenteralIntramuscularOphthalmicIntradermal

Species Affected

Dog 9,322

Unknown 759

Cattle 677

Cat 397

Horse 199

Human 178

Sheep 34

Pig 25

Goat 21

Rabbit 9

Most Affected Breeds

Retriever - Labrador 1,293

Unknown 1,049

Crossbred Canine/dog 565

Shepherd Dog - German 418

Chihuahua 356

Retriever - Golden 295

Terrier - Yorkshire 293

Pit Bull 278

Boxer (German Boxer) 273

Shih Tzu 267

Most Reported Reactions

Lack of efficacy (endoparasite) - heartworm 1,739

Emesis 1,470

Vomiting 1,369

INEFFECTIVE, HEARTWORM LARVAE 966

Lethargy (see also Central nervous system depression in 'Neurological') 960

Ataxia 674

Lack of efficacy - NOS 564

Diarrhoea 530

Seizure NOS 460

Lack of efficacy (ectoparasite) - flea 426

Death 372

Other abnormal test result NOS 345

Outcome Breakdown

Recovered/Normal

3,468 (34.2%)

Outcome Unknown

3,068 (30.2%)

Ongoing

2,516 (24.8%)

Recovered with Sequela

455 (4.5%)

Died

439 (4.3%)

Euthanized

203 (2.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.