Drug profile

The FDA adverse-event record for Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement

30 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement. Species, reactions, and outcomes follow.

#1449 of 2,679
by report volume (all drugs)
30
adverse-event reports
3.3%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement ranks #1440 of 2679 by total reports (30). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1440
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement has 30 reports now versus 23 in that prior snapshot: 7 more (30.4%).

Report change
+7
Death-coded reports
+0
Death-coded share
−1.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement changes

Signature read: Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement's 3.3% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
30
Total Reports
1
Deaths Reported
3.3%
Death-coded share of reports

Active Ingredients

Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement

Administration Routes

UnknownOral

Species Affected

Dog 30

Most Affected Breeds

Retriever - Labrador 15
Retriever - Golden 3
Havanese 2
Shepherd Dog - Belgian (unspecified) 2
Spaniel - Springer English 2
Shepherd Dog - German 1
Great Pyrenees 1
Dog (unknown) 1
Shepherd (unspecified) 1
Bulldog - French 1

Most Reported Reactions

Vomiting 7
Arthritis 5
Limping 5
Other abnormal test result NOS 3
Lack of efficacy (bacteria) - Borrelia 3
Lack of efficacy (endoparasite) - heartworm 3
Lack of efficacy - NOS 3
Pruritus 3
Exudative skin condition 3
Erythema (for urticaria see Immune SOC) 3
Comedo/blackhead 3
Ear canal erythema 3

Outcome Breakdown

Outcome Unknown
12 (40.0%)
Recovered/Normal
9 (30.0%)
Ongoing
8 (26.7%)
Died
1 (3.3%)

Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Glucosamine/ Chondroitin/ Avocado/Soybean Unsaponifiables/ Decaffeinated Tea Joint Supplement (#1449 of 2,679 by report volume); death-coded 3.3%. PlainBreed drug row · death-coded share stamp 3.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →