Drug profile

The FDA adverse-event record for Frunevetmab

7,813 FDA reports name Frunevetmab, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#34 of 2,679
by report volume (all drugs)
7,813
adverse-event reports
10.4%
death-coded share
Cat
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Frunevetmab ranks #34 of 2679 by total reports (7,813) and #530 of 1130 by death-coded share (10.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#34
This drug, reports of 2679
#530
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Frunevetmab has 7,813 reports now versus 7,409 in that prior snapshot: 404 more (5.5%).

Report change
+404
Death-coded reports
+27
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Frunevetmab changes

Signature read: death-coded report count at 815 is the most distinctive stamp on Frunevetmab's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
7,813
Total Reports
815
Deaths Reported
10.4%
Death-coded share of reports

Active Ingredients

Frunevetmab

Administration Routes

SubcutaneousUnknownParenteralOtherSubconjunctivalOralTopicalIntramuscularOphthalmicIntradermal

Species Affected

Cat 7,616
Unknown 107
Human 81
Dog 6
Lynx 1
Other 1
Cougar 1

Most Affected Breeds

Domestic Shorthair 4,660
Cat (other) 875
Domestic Longhair 692
Domestic Mediumhair 414
Siamese 207
Unknown 195
Maine Coon 139
Cat (unknown) 85
Ragdoll 77
Persian 62

Most Reported Reactions

Skin scab 837
Vomiting 799
Lethargy (see also Central nervous system depression in Neurological) 695
Lack of efficacy - NOS 643
Pruritus 637
Weight loss 499
Death by euthanasia 498
Diarrhoea 444
Not eating 428
Skin lesion NOS 369
Decreased appetite 347
Partial lack of efficacy 322

Outcome Breakdown

Ongoing
4,873 (63.2%)
Outcome Unknown
1,013 (13.1%)
Recovered/Normal
999 (13.0%)
Euthanized
504 (6.5%)
Died
311 (4.0%)
Recovered with Sequela
5 (0.1%)

Frunevetmab: high report volume in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Frunevetmab, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Frunevetmab (#34 of 2,679 by report volume); death-coded 10.4%. PlainBreed drug row · death-coded report count stamp 815 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →