Drug profile

The FDA adverse-event record for Bordetella Bronchiseptica Vaccine, Avirulent Live Culture

633 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Bordetella Bronchiseptica Vaccine, Avirulent Live Culture. See the species affected, top reactions, and outcomes below.

633
adverse-event reports
6.8%
death-coded share
Dog
most-reported species
147
Vomiting - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
633
Total Reports
43
Deaths Reported
6.8%
Death Rate

Active Ingredients

Bordetella Bronchiseptica Vaccine, Avirulent Live Culture

Administration Routes

OralUnknownSubcutaneousBuccalParenteralNasalTopicalOther

Species Affected

Dog 633

Most Affected Breeds

Retriever - Labrador 98
Retriever - Golden 53
Shepherd Dog - Australian 32
Chihuahua 27
Shih Tzu 26
Terrier - Yorkshire 22
Pug 15
Dachshund (unspecified) 15
Shepherd Dog - German 15
Boxer (German Boxer) 14

Most Reported Reactions

Vomiting 147
Lack of efficacy - NOS 76
Lack of efficacy (virus NOS) 71
Other abnormal test result NOS 61
Cough 55
Diarrhoea 49
Lethargy (see also Central nervous system depression in 'Neurological') 47
Lack of efficacy (virus) - NOS 44
Lethargy (see also Central nervous system depression in Neurological) 41
Facial swelling (see also 'Skin') 32
Anaphylaxis 29
Not eating 28

Outcome Breakdown

Outcome Unknown
322 (50.8%)
Recovered/Normal
184 (29.0%)
Ongoing
84 (13.2%)
Died
24 (3.8%)
Euthanized
19 (3.0%)
Recovered with Sequela
1 (0.2%)

Bordetella Bronchiseptica Vaccine, Avirulent Live Culture Adverse Event Insights

633 reports name Bordetella Bronchiseptica Vaccine, Avirulent Live Culture; 43 recorded a death outcome (6.8% of reported events, not a population-level mortality rate). Active ingredient: Bordetella Bronchiseptica Vaccine, Avirulent Live Culture. Administration routes: Oral, Unknown, Subcutaneous, Buccal.

By species: Dog (633 reports). By breed: Retriever - Labrador (98), Retriever - Golden (53), Shepherd Dog - Australian (32).

Leading clinical signs: Vomiting (147), Lack of efficacy - NOS (76), Lack of efficacy (virus NOS) (71), Other abnormal test result NOS (61). Outcome, 634 coded reports: Outcome Unknown leads at 50.8%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.