Anti-Diarrheal

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25 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
25
Total Reports
7
Deaths Reported
2800.0%
Death Rate

Active Ingredients

Anti-Diarrheal

Administration Routes

UnknownOralParenteral

Species Affected

Dog 22
Cat 3

Most Affected Breeds

Retriever - Labrador 3
Terrier - Yorkshire 3
Bulldog 2
Shih Tzu 2
Domestic Shorthair 2
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1
Shepherd Dog - German 1
Terrier (unspecified) 1
Schnauzer (unspecified) 1
Pinscher - Miniature 1

Most Reported Reactions

Diarrhoea 15
Lethargy (see also Central nervous system depression in 'Neurological') 10
Vomiting 9
Death by euthanasia 6
Decreased appetite 5
Anaemia NOS 5
Elevated serum alkaline phosphatase (SAP) 5
Elevated alanine aminotransferase (ALT) 5
Anorexia 4
Other abnormal test result NOS 3
Leucocytosis NOS 3
Fever 3

Outcome Breakdown

Ongoing
11 (44.0%)
Euthanized
6 (24.0%)
Outcome Unknown
5 (20.0%)
Recovered/Normal
2 (8.0%)
Died
1 (4.0%)

Data Summary

Metric Value
Total adverse event reports 25
Reports involving death 7
Case-fatality rate (reported events) 2800.0%
Distinct species in reports 2
Distinct breeds in reports 18
Distinct reactions reported 20
Active ingredients on file 1

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER). Counts reflect voluntary reports only.

Anti-Diarrheal Adverse Event Insights

The FDA Center for Veterinary Medicine database currently holds 25 adverse event reports referencing Anti-Diarrheal, including 7 reports in which the animal died — a 2800.0% case-fatality figure among reported events only, not a population-level mortality rate. Active ingredient on file: Anti-Diarrheal. Reported administration routes include Unknown, Oral, Parenteral. These numbers reflect voluntary submissions from pet owners, veterinarians, and manufacturers and therefore under-represent mild events and over-represent severe ones — a pattern the FDA has documented repeatedly for pharmacovigilance datasets.

The species most frequently named in Anti-Diarrheal reports are Dog (22 reports), Cat (3 reports), with Dog accounting for the largest share. Within those species, Retriever - Labrador (3), Terrier - Yorkshire (3), Bulldog (2) appear most often — though breed popularity and ownership density shape these counts as much as any drug-specific sensitivity. This distribution matters because the same active ingredient can behave very differently across body sizes, ages, and species physiology.

The most commonly reported clinical signs associated with Anti-Diarrheal are Diarrhoea (15), Lethargy (see also Central nervous system depression in 'Neurological') (10), Vomiting (9), Death by euthanasia (6). Of the 25 reports with a coded outcome, Ongoing is the leading category at 44.0%. Because FDA adverse event data describes correlation rather than causation, these figures are best used to frame informed questions with a veterinarian and to compare reporting patterns across related products — not as a standalone safety verdict on Anti-Diarrheal.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial