Alfaxalone

907 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

907

Total Reports

183

Deaths Reported

2020.0%

Death Rate

Active Ingredients

Alfaxalone

Administration Routes

IntravenousUnknownIntramuscularSubcutaneousParenteralOralTopicalIntraperitonealIntrauterineOphthalmic

Species Affected

Dog 442

Cat 407

Rabbit 22

Unknown 11

Guinea Pig 4

Human 4

Other Reptiles 2

Mouse 2

Lizard 2

Ferret 2

Most Affected Breeds

Domestic Shorthair 205

Unknown 81

Retriever - Labrador 39

Domestic Longhair 39

Chihuahua 34

Dog (unknown) 22

Domestic Mediumhair 21

Cat (other) 20

Cat (unknown) 19

Crossbred Canine/dog 18

Most Reported Reactions

Death 134

Cardiac arrest 74

Bradycardia 71

Lack of efficacy - NOS 59

Vomiting 57

Not eating 57

Hypotension 50

Diarrhoea 49

Tachycardia 48

Apnoea 46

Vocalisation 46

Cyanosis 44

Outcome Breakdown

Recovered/Normal

430 (47.4%)

Ongoing

179 (19.7%)

Died

145 (16.0%)

Outcome Unknown

107 (11.8%)

Euthanized

38 (4.2%)

Recovered with Sequela

9 (1.0%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.