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Breed profile · FDA CVM July 2026 extract

Hampshire Down adverse-event record

Adverse-event filings for Hampshire Down (Sheep) in the FDA Center for Veterinary Medicine openFDA extract. Browse sheep breeds, reactions, and outcomes below.

#453 of 510
by report volume (all breeds)
8
FDA CVM reports on file
50.0%
death-coded share of reports
4
Death - top reaction

How the 8 reports break down

By recorded gender -- every report on file for Hampshire Down, no filtering.

Annual report volume

Annual adverse-event report trend Yearly FDA CVM adverse-event report counts for this breed. 2 1.5 1 0.5 0 2012 2013 2014 2015 2019 2020 2024 Reports filed Death-coded reports
Annual report volume for Hampshire Down drawn from FDA CVM filings.

Data updated September 2026

The verdict

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Hampshire Down ranks #449 of 510 by total reports (8). Death-coded-share rank requires at least 50 reports. National dual: Retriever - Labrador is #1 of 510 by total adverse-event reports (93,675) at death-coded-share rank 195 of 275 breeds with at least 50 reports (3.7%); separately, Atlantic Salmon (Salmo salar) is #1 highest death-coded share at 99.0% (report rank #233).

93,675
Retriever - Labrador reports (#1)
99.0%
Atlantic Salmon (Salmo salar) death share (#1)
#449
This breed, reports of 510

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hampshire Down has 8 reports now versus 8 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hampshire Down changes

Total Reports

8

Low report volume

Deaths Reported

4

of 8 reports

Death-coded share of reports

50.0%

50.0% death-coded

Avg Age at Report

2.1 yr

66.3 kg avg weight

Death-Coded Outcome Share

Hampshire Down death-coded reports 50.0%
Cross-breed median

50.0% of 8 hampshire down reports involved a death outcome.

How to read this number

Read alongside breed popularity, veterinary access, and owner awareness, these shape how many events ever reach the FDA. The comparison line marks the cross-breed median death-coded share (4.8%) among breeds with 50 or more reports; values above it suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.

Average weight at time of report: 66.3 kg (146.2 lbs)

Top Reported Reactions

Death 4
Anaphylactic-type reaction 2
Ruminal bloat 2
Injection site oedema 2
Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders') 1

Most Referenced Drugs

Ceftiofur Crystalline Free Acid 2
Tilmicosin Phosphate 1
Monensin Sodium 1
Enrofloxacin 1
Chlortetracycline 1

Outcome Breakdown

Died
4 (40.0%)
Recovered/Normal
4 (40.0%)
Outcome Unknown
2 (20.0%)

Gender Distribution

Female 4 (50.0%)
Male 2 (25.0%)
Mixed 1 (12.5%)
Unknown 1 (12.5%)

Reports by Year

Year Reports Trend
2012 1
2013 1
2014 1
2015 1
2019 1
2020 2
2024 1

Hampshire Down: high death-coded share in the FDA CVM extract

Signature read: 8 reports place Hampshire Down in the lower third of breed filing volume (#453 of 510). According to FDA CVM filings indexed on PlainBreed as of July 2026 extract, Hampshire Down sits at #453 of 510 by report volume among all breeds and #5 of 9 among sheep breeds, with 8 reports and 4 (50.0%) death-coded. Mean age at report: 2.1 years, average weight 66.3 kg (146.2 lbs).

Top reported signs: Death (4), Anaphylactic-type reaction (2), Ruminal bloat (2). Most-referenced drug: Ceftiofur Crystalline Free Acid (2 reports), followed by Tilmicosin Phosphate (1) and Monensin Sodium (1).

Outcome coding on 10 status-recorded reports is dominated by Died (40.0%). Annual submissions ranged 1-2,024 across 7 years on file.

Sheep Breeds With a Similar Report Volume

Showing 6 of 8 sheep breeds in our dataset, ranked by closest report volume.

Nationwide breeds with similar profiles

Sparse-volume peer sets for Hampshire Down drawn from openFDA outside the Sheep family so the neighborhoods are not species containment (the similar-volume list above stays within species).

What to do with this sheep

A report does not prove a drug caused the reaction, and popular breeds simply generate more reports.

Frequently Asked Questions

How many FDA adverse event reports involve Hampshire Down?
There are 8 adverse event reports involving Hampshire Down in the FDA database, of which 4 were death-coded (50.0% of those reports). That is a share of REPORTED events, not a mortality rate for the breed: adverse events reach the FDA when something goes wrong, so the denominator is reports, never the population of animals. According to the same FDA CVM extract, Hampshire Down ranks #453 of 510 by report volume among all breeds PlainBreed indexes (#5 of 9 among sheep breeds).
Where does Hampshire Down sit among other breeds in PlainBreed's corpus?
According to FDA CVM report volume, Hampshire Down is #453 of 510 breeds indexed on PlainBreed (same ordering as the most-reported-breeds ranking). Inside Sheep, it is #5 of 9. It has fewer than 50 reports, so it is outside the death-rate ranking cohort (≥50 reports). These are placement ranks in the reporting corpus, not clinical risk scores.
What are the most common adverse reactions reported for Hampshire Down?
The most commonly reported adverse reactions for Hampshire Down are Death (4 reports), Anaphylactic-type reaction (2 reports), Ruminal bloat (2 reports), Injection site oedema (2 reports), Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders') (1 reports).
What drugs are most frequently associated with Hampshire Down adverse events?
The drugs most frequently referenced in Hampshire Down adverse event reports are Ceftiofur Crystalline Free Acid (2 reports), Tilmicosin Phosphate (1 reports), Monensin Sodium (1 reports), Enrofloxacin (1 reports), Chlortetracycline (1 reports).
What is the average age of Hampshire Down in adverse event reports?
The average age of Hampshire Down at the time of adverse event reports is 2.1 years, with an average weight of 66.3 kg (146.2 lbs).

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hampshire Down (Sheep), extract as of July 2026 extract. 8 reports · 4 death-coded (50.0% of reports, not a mortality rate) · #453 of 510 by volume.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →