Total Reports
8
FDA CVM filings
Sheep /
2026 FDA CVM data 8 reports on file official source
Hampshire Down — FDA Adverse Event Profile
Adverse-event records and label data for Hampshire Down (Sheep), sourced from the FDA Center for Veterinary Medicine. Refreshed as new reports are filed. Cite PlainBreed when reusing this analysis.
Hampshire Down (Sheep) has 8 FDA adverse event reports on record, with 4 deaths reported (5000.0% death rate) — ranking #448 by report volume. The most frequently reported reaction is Death (4 cases). The top associated drug is Ceftiofur Crystalline Free Acid. Average age at report: 2.1 years.
Deaths Reported
4
of 8 reports
Death Rate
5000.0%
death-coded share
Avg Age at Report
2.1 yr
66.3 kg avg weight
Death-Coded Outcome Share
Hampshire Down death-coded reports 100.0%
Database median
5000.0% of 8 reports involved a death outcome. Read alongside breed popularity, veterinary access, and owner awareness — these shape how many events ever reach the FDA. The 12% comparison line is the rough cross-breed median in the FDA CVM database; values above suggest higher reporting bias toward severe outcomes, not necessarily higher true mortality.
Average weight at time of report: 66.3 kg (146.2 lbs)
Top Reported Reactions
Death 4
Anaphylactic-type reaction 2
Ruminal bloat 2
Injection site oedema 2
Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders') 1
Laboured breathing 1
Not eating 1
Foam in the trachea 1
Pulmonary oedema 1
Pulmonary disorder NOS 1
Hyperaemia 1
Periorbital oedema 1
Overdose 1
Lack of efficacy - NOS 1
Cellulitis 1
Most Referenced Drugs
Ceftiofur Crystalline Free Acid 2
Tilmicosin Phosphate 1
Monensin Sodium 1
Enrofloxacin 1
Chlortetracycline 1
Progesterone 1
Ketoprofen;Tulathromycin 1
Albendazole 1
Doramectin 1
Outcome Breakdown
Died
4 (40.0%)
Recovered/Normal
4 (40.0%)
Outcome Unknown
2 (20.0%)
Gender Distribution
Female 4 (50.0%)
Male 2 (25.0%)
Mixed 1 (12.5%)
Unknown 1 (12.5%)
Reports by Year
| Year | Reports | Trend |
|---|---|---|
| 2012 | 1 | |
| 2013 | 1 | |
| 2014 | 1 | |
| 2015 | 1 | |
| 2019 | 1 | |
| 2020 | 2 | |
| 2024 | 1 | |
Hampshire Down Pet Health Insights
Across the FDA Center for Veterinary Medicine adverse event database, Hampshire Down accounts for 8 submitted reports and currently ranks #448 by report volume within the sheep population. Of those reports, 4 involved a death outcome — a 5000.0% case-fatality figure calculated directly from the underlying FDA records rather than from external mortality studies. The mean age at time of reporting is 2.1 years, with an average recorded body weight of 66.3 kg (146.2 lbs). These figures reflect the voluntary reporting pool only and should be read alongside breed popularity, veterinary access, and owner awareness — all of which shape how many events ever reach the FDA.
The most frequently reported clinical signs for Hampshire Down are Death (4 reports), Anaphylactic-type reaction (2 reports), Ruminal bloat (2 reports), together capturing a substantial share of the top-reaction traffic seen in this breed's record. On the product side, Ceftiofur Crystalline Free Acid appears in 2 reports and is the single most-referenced drug, followed by Tilmicosin Phosphate (1) and Monensin Sodium (1). Counts like these surface which therapeutic classes dominate the reporting stream — useful context when comparing reactions across breeds of the same sheep species.
Outcome coding on the 10 reports with a recorded status is dominated by Died (40.0% of coded outcomes). Annual submission volume ranges from 2,012 to 2,024 reports across the 7 years on file, indicating the reporting trend is shaped as much by awareness cycles as by underlying clinical events. Because FDA adverse event reports describe correlation rather than causation, these numbers are most useful as a signal of where to ask further questions with a veterinarian — not as a standalone risk score for any individual sheep.
Understanding Hampshire Down Adverse Event Data
Hampshire Down has 8 adverse event reports on file. Lower report volumes may reflect a less common breed, lower reporting rates, or genuinely fewer adverse events.
The 5000.0% death rate is above average, though this statistic should be interpreted cautiously. Death reports may be overrepresented because serious outcomes are more likely to be reported than mild reactions.
The most frequently referenced drug in adverse reports is Ceftiofur Crystalline Free Acid, appearing in 2 reports. This may indicate widespread use of the medication rather than a specific safety concern for Hampshire Down.
Other Sheep Breeds
Frequently Asked Questions
How many FDA adverse event reports involve Hampshire Down? ▼
There are 8 adverse event reports involving Hampshire Down in the FDA database, with 4 reports involving death (5000.0% death rate). Hampshire Down ranks #448 by report volume.
What are the most common adverse reactions reported for Hampshire Down? ▼
The most commonly reported adverse reactions for Hampshire Down are Death (4 reports), Anaphylactic-type reaction (2 reports), Ruminal bloat (2 reports), Injection site oedema (2 reports), Collapse NOS (see also 'Cardio-vascular' and 'Neurological disorders') (1 reports).
What drugs are most frequently associated with Hampshire Down adverse events? ▼
The drugs most frequently referenced in Hampshire Down adverse event reports are Ceftiofur Crystalline Free Acid (2 reports), Tilmicosin Phosphate (1 reports), Monensin Sodium (1 reports), Enrofloxacin (1 reports), Chlortetracycline (1 reports).
What is the average age of Hampshire Down in adverse event reports? ▼
The average age of Hampshire Down at the time of adverse event reports is 2.1 years, with an average weight of 66.3 kg (146.2 lbs).
Does a high number of adverse event reports mean Hampshire Down is unhealthy? ▼
No. FDA adverse event reports are voluntarily submitted and do not prove causation. Popular breeds with more veterinary visits tend to have more reports. The data reflects reporting patterns, not actual incidence rates. Always consult a veterinarian for health decisions.
Where does this Hampshire Down safety data come from? ▼
All data comes from the FDA Center for Veterinary Medicine's adverse event reporting system. Pet owners, veterinarians, and manufacturers voluntarily submit reports about adverse events potentially linked to animal drugs and other products.
Guides & Resources
Understanding Adverse Events
What FDA reports are and how they are collected
Breed-Specific Risks
Why some breeds appear in more adverse event reports
Pet Medication Safety
Evaluating medication risks using FDA data
Most Reported Medications
Drugs that appear most in adverse event reports
How FDA CVM Tracks Events
The reporting process and database limitations
Related Data Sources
Data Sources & Methodology
Adverse event data sourced from the FDA Center for Veterinary Medicine via the openFDA Animal & Veterinary Adverse Events API. Reports are voluntarily submitted by pet owners, veterinarians, and product manufacturers.
Hampshire Down ranks #448 by total report volume. Death rate (5000.0%) reflects the proportion of reports involving death and should not be interpreted as a breed-specific mortality rate. Reporting biases, breed popularity, and veterinary access all influence report counts.
Read our methodology — how this data is sourced, computed, and verified.
Related
Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial