Drug profile

The FDA adverse-event record for Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3

17 FDA reports name Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3, a lower-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#1994 of 2,679
by report volume (all drugs)
17
adverse-event reports
5.9%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3 ranks #1937 of 2679 by total reports (17). Death-coded-share rank requires at least 50 reports. National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1937
This drug, reports of 2679

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3 has 17 reports now versus 17 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3 changes

Signature read: death-coded report count at 1 is the most distinctive stamp on Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
17
Total Reports
1
Deaths Reported
5.9%
Death-coded share of reports

Active Ingredients

Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3

Administration Routes

OralUnknown

Species Affected

Dog 17

Most Affected Breeds

Retriever - Labrador 3
Terrier - Rat 2
Crossbred Canine/dog 2
Bulldog 2
Poodle (unspecified) 1
Shepherd Dog - Australian 1
Beagle 1
Pug 1
Collie - Border 1
Terrier - Irish Soft-coated Wheaten 1

Most Reported Reactions

Lethargy (see also Central nervous system depression in 'Neurological') 4
Vomiting 4
Elevated creatinine 3
Not eating 3
Panting 3
Weight loss 2
Pain NOS 2
Diarrhoea 2
Allergy NOS 2
Seizure NOS 1
Elevated alanine aminotransferase (ALT) 1
Elevated serum alkaline phosphatase (SAP) 1

Outcome Breakdown

Recovered/Normal
6 (35.3%)
Ongoing
6 (35.3%)
Outcome Unknown
4 (23.5%)
Died
1 (5.9%)

Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Zanthin,Proprietary Hyaluronic Acid, Akba Boswellia Serrata, Biovaflex, Vitamin D3 (#1994 of 2,679 by report volume); death-coded 5.9%. PlainBreed drug row · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →