Xylazine

448 adverse event reports submitted to the FDA

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.

448

Total Reports

145

Deaths Reported

3240.0%

Death Rate

Active Ingredients

Xylazine

Administration Routes

UnknownIntravenousIntramuscularParenteralIntraperitonealSubcutaneousOralOther

Species Affected

Horse 149

Dog 116

Cat 80

Unknown 36

Mouse 18

Cattle 16

Rat 7

Pig 6

Goat 4

Human 4

Most Affected Breeds

Unknown 92

Quarter Horse 44

Domestic Shorthair 39

Horse (unknown) 27

Cat (unknown) 25

Dog (unknown) 22

Retriever - Labrador 13

Shepherd Dog - German 9

Horse (other) 7

Appaloosa 6

Most Reported Reactions

Death 94

Lack of efficacy - NOS 91

INEFFECTIVE, SEDATION 58

INEFFECTIVE, ANESTHESIA 36

Death by euthanasia 29

Seizure NOS 26

Color, Abnormal 19

Recovery prolonged 18

Anorexia 17

Vomiting 16

Fever 16

Lethargy (see also Central nervous system depression in 'Neurological') 16

Outcome Breakdown

Recovered/Normal

213 (50.5%)

Died

99 (23.5%)

Euthanized

47 (11.1%)

Outcome Unknown

42 (10.0%)

Ongoing

19 (4.5%)

Recovered with Sequela

2 (0.5%)

Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.