Drug profile

The FDA adverse-event record for Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride

317 FDA reports name Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride, a high-volume drug in the CVM extract. Species, reactions, and outcomes follow.

#401 of 2,679
by report volume (all drugs)
317
adverse-event reports
0.6%
death-coded share
Unknown
most-reported species
Verify with FDA CVM →

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride ranks #400 of 2679 by total reports (317) and #1091 of 1130 by death-coded share (0.6%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#400
This drug, reports of 2679
#1091
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride has 317 reports now versus 304 in that prior snapshot: 13 more (4.3%).

Report change
+13
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride changes

Signature read: Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride's 0.6% death-coded share is among the lowest in the openFDA drug corpus.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
317
Total Reports
2
Deaths Reported
0.6%
Death-coded share of reports

Active Ingredients

Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride

Administration Routes

UnknownIntravenousSubcutaneous

Species Affected

Unknown 300
Dog 12
Horse 3
Cat 2

Most Affected Breeds

Unknown 300
Quarter Horse 3
Retriever - Labrador 2
Dog (other) 1
Crossbred Canine/dog 1
Domestic Shorthair 1
Poodle - Toy 1
Poodle - Miniature 1
Dog (unknown) 1
Retriever - Golden 1

Most Reported Reactions

Containers, Damaged 286
Containers, Leaking 182
Weight loss 7
Underfilling, Container 6
Dehydration 6
Neutrophilia 6
Abnormal ultrasound finding 6
Prolonged capillary refill time 6
Other abnormal test result NOS 5
Not eating 4
Monocytosis 4
Hyperglycaemia 4

Outcome Breakdown

Outcome Unknown
12 (63.2%)
Recovered/Normal
3 (15.8%)
Euthanized
1 (5.3%)
Died
1 (5.3%)
Ongoing
1 (5.3%)
Recovered with Sequela
1 (5.3%)

Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride: low death-coded share in the FDA AER row

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

High-volume nationwide drug peers

Two openFDA-derived peer sets for Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

  • Compare Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride's report volume and death-coded share against similar drugs nationwide. See similar drugs
  • Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
  • Browse the full drug directory to compare report counts across products. All drugs

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Water, Sodium Chloride, Sodium Gluconate, Sodium Acetate Trihydrate, Potassium Chloride, Magnesium Chloride (#401 of 2,679 by report volume); death-coded 0.6%. PlainBreed drug row · death-coded share stamp 0.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →