Drug profile

The FDA adverse-event record for Vitamin Supplement

54 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Vitamin Supplement. Species, reactions, and outcomes follow.

#1076 of 2,679
by report volume (all drugs)
54
adverse-event reports
7.4%
death-coded share
Dog
most-reported species

Corpus placement

According to the FDA Center for Veterinary Medicine openFDA adverse-event extract, Vitamin Supplement ranks #1065 of 2679 by total reports (54) and #673 of 1130 by death-coded share (7.4%). National dual: Milbemycin Oxime + Spinosad is #1 of 2679 drugs by total adverse-event reports (149,624) at death-coded-share rank 965 of 1130 drugs with at least 50 reports (2.3%); separately, Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) is #1 highest death-coded share at 97.8% (report rank #821).

149,624
Milbemycin Oxime + Spinosad reports (#1)
97.8%
Atlantic Salmon Transgenic Whole (Opafp-Ghc2 Rdna Construct Inserted Into The A-Locus In The Eo-1A Lineage) death share (#1)
#1065
This drug, reports of 2679
#673
This drug, death share of 1130

Report volume reflects how common a breed or drug is and how often owners and vets file — not actual risk. Death-coded share ranks are limited to entries with enough reports to be meaningful. The two maps do not agree at #1.

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vitamin Supplement has 54 reports now versus 54 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vitamin Supplement changes

Signature read: death-coded share at 7.4% is the most distinctive stamp on Vitamin Supplement's FDA AER row.

Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
54
Total Reports
4
Deaths Reported
7.4%
Death-coded share of reports

Active Ingredients

Vitamin Supplement

Administration Routes

OralUnknownOtherParenteral

Species Affected

Dog 43
Cat 5
Human 4
Cattle 1
Goat 1

Most Affected Breeds

Chihuahua 4
Retriever - Labrador 4
Unknown 4
Domestic Shorthair 3
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 2
Shepherd Dog - Australian 2
Shepherd Dog - German 2
Pit Bull 2
Shih Tzu 2
Dachshund (unspecified) 2

Most Reported Reactions

Vomiting 15
Lethargy (see also Central nervous system depression in 'Neurological') 11
Diarrhoea 11
Ataxia 6
Behavioural disorder NOS 5
Decreased appetite 5
Weight loss 5
Neutropenia 4
Panting 4
Urine abnormalities NOS 4
Decreased haematocrit 4
Other abnormal test result NOS 3

Outcome Breakdown

Recovered/Normal
21 (38.9%)
Outcome Unknown
19 (35.2%)
Ongoing
10 (18.5%)
Euthanized
2 (3.7%)
Died
2 (3.7%)

Vitamin Supplement Adverse Event Insights

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Nationwide drugs with similar profiles

Two openFDA-derived peer sets for Vitamin Supplement, both floored at ≥50 reports so the neighborhoods stay in the advertised mass.

What to do with this drug

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vitamin Supplement (#1076 of 2,679 by report volume); death-coded 7.4%. PlainBreed drug row · death-coded share stamp 7.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →