Drug profile

The FDA adverse-event record for Vitamin D

45 adverse-event reports submitted to the FDA Center for Veterinary Medicine reference Vitamin D. See the species affected, top reactions, and outcomes below.

45
adverse-event reports
11.1%
death-coded share
Human
most-reported species
16
Accidental exposure - top reaction
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Important: Adverse event reports do not establish that a drug caused or contributed to the event. Consult your veterinarian before making treatment decisions.
45
Total Reports
5
Deaths Reported
11.1%
Death Rate

Active Ingredients

Vitamin D

Administration Routes

UnknownOral

Species Affected

Human 32
Dog 8
Cat 2
Llama 1
Pig 1
Cattle 1

Most Affected Breeds

Unknown 33
Domestic Shorthair 2
Schnauzer (unspecified) 2
Shepherd Dog - German 1
Pig (unknown) 1
Mixed (Cattle) 1
Terrier - Cairn 1
Terrier - Silky 1
Terrier - American Staffordshire 1
Retriever - Labrador 1

Most Reported Reactions

Accidental exposure 16
Diarrhoea 6
Lethargy (see also Central nervous system depression in 'Neurological') 4
Headache 4
Not eating 4
Nausea 3
Dizziness 3
Mental impairment NOS 3
Vocalisation 3
Seizure NOS 3
Death 2
Anorexia 2

Outcome Breakdown

Recovered/Normal
20 (42.6%)
Outcome Unknown
17 (36.2%)
Ongoing
5 (10.6%)
Died
3 (6.4%)
Euthanized
2 (4.3%)

Vitamin D Adverse Event Insights

45 reports name Vitamin D; 5 recorded a death outcome (11.1% of reported events, not a population-level mortality rate). Active ingredient: Vitamin D. Administration routes: Unknown, Oral.

By species: Human (32 reports), Dog (8 reports), Cat (2 reports). By breed: Unknown (33), Domestic Shorthair (2), Schnauzer (unspecified) (2).

Leading clinical signs: Accidental exposure (16), Diarrhoea (6), Lethargy (see also Central nervous system depression in 'Neurological') (4), Headache (4). Outcome, 47 coded reports: Recovered/Normal leads at 42.6%.

Read these counts as reporting volume, not risk: per our methodology, a widely-prescribed drug will rack up more raw FDA reports in a given year than a rarely-used one at an identical true rate, so we recommend comparing within similar-exposure products rather than across the full 2025 catalog.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.